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单卵双胞胎胼胝体的磁共振成像形态学

Magnetic resonance imaging morphology of the corpus callosum in monozygotic twins.

作者信息

Oppenheim J S, Skerry J E, Tramo M J, Gazzaniga M S

机构信息

Department of Neurology, Cornell University Medical College, New York, NY.

出版信息

Ann Neurol. 1989 Jul;26(1):100-4. doi: 10.1002/ana.410260117.

DOI:10.1002/ana.410260117
PMID:2774498
Abstract

Recent reports describe wide variations in the size and shape of the human corpus callosum. To investigate genetic influences on this variability, magnetic resonance images from 5 pairs of monozygotic twins and 10 unrelated control subjects were analyzed. Measurements of size and shape revealed greater similarity in twin pairs than in randomly paired controls. The results are consistent with the view that the anatomy of the corpus callosum, while clearly influenced by nongenetic factors, is under considerable genetic control.

摘要

最近的报告描述了人类胼胝体在大小和形状上存在很大差异。为了研究这种变异性的遗传影响,分析了来自5对同卵双胞胎和10名无关对照受试者的磁共振图像。大小和形状的测量结果显示,双胞胎对之间的相似性高于随机配对的对照组。这些结果与以下观点一致,即胼胝体的解剖结构虽然明显受到非遗传因素的影响,但也受到相当程度的遗传控制。

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