Lakshminarayanaiah N, Murayama K
J Membr Biol. 1975;23(3-4):279-92. doi: 10.1007/BF01870254.
The resting membrane potential data existing in the literature for the giant axon of the squid, frog muscle and barnacle muscle have been analyzed from the standpoint of the theory of membrane potential due to Kobatake and co-workers. The average values derived for the effective charge density phi chi (where phi is a constant, 0 less than phi less than 1, and represents the fraction of counterions that are free, and chi is the stoichiometric charge density in the membrane) present on the different biomembranes existing in their normal ionic environment are 0.3, 0.325 and 0.17 M for the squid axon, frog and barnacle muscles, respectively. On the assumption that the values of phi are 0.4 and 0.2 for nerve and muscle membranes, respectively, values of 0.75, 1.62 and 0.85 M have been derived for the stoichiometric charge density (chi) present in the respective biological membranes. These correspond to 1 negative charge per 222, 103 and 195 A2 of the membrane area of the squid axon, frog and barnacle muscles, respectively.
已从儿玉武夫及其同事的膜电位理论角度，分析了文献中存在的关于乌贼巨轴突、青蛙肌肉和藤壶肌肉的静息膜电位数据。在正常离子环境下，乌贼轴突、青蛙和藤壶肌肉等不同生物膜上存在的有效电荷密度φχ（其中φ为常数，0＜φ＜1，表示自由反离子的比例，χ为膜中的化学计量电荷密度）的平均值分别为0.3、0.325和0.17M。假设神经膜和肌肉膜的φ值分别为0.4和0.2，则相应生物膜中存在的化学计量电荷密度（χ）值分别为0.75、1.62和0.85M。这些分别对应于乌贼轴突、青蛙和藤壶肌肉膜面积每222、103和195 A2有1个负电荷。
