Surmont Veerle F, van Klaveren Rob J, Nowak Peter J C M, Zondervan Pieter E, Hoogsteden Henk C, van Meerbeeck Jan P
Department of Pulmonology, Respiratory Oncology Unit, University Hospital Gasthuisberg, Herestraat 49, B-3000 Leuven, Belgium.
Lung Cancer. 2002 May;36(2):207-11. doi: 10.1016/s0169-5002(01)00465-2.
Pulmonary blastoma (PB) is a rare malignant tumor of the lung. Treatment is primarily surgical, although, combination chemotherapy has been reported to result in objective responses in inoperable tumors or after incomplete resections. To our knowledge, this is the first report of a very radiosensitive PB, which showed major tumor reduction after several fractions of radiotherapy without further tumor regression after additional chemotherapy with cisplatin and etoposide. The literature on the treatment of PB is reviewed.
肺母细胞瘤(PB)是一种罕见的肺部恶性肿瘤。治疗主要以手术为主,不过,据报道联合化疗对无法手术的肿瘤或不完全切除术后的肿瘤可产生客观反应。据我们所知,这是首例关于对放疗非常敏感的肺母细胞瘤的报告,该病例在经过几次放疗后肿瘤显著缩小,而在随后使用顺铂和依托泊苷进行化疗后肿瘤未进一步消退。本文对肺母细胞瘤的治疗文献进行了综述。