• 文献检索
  • 文档翻译
  • 深度研究
  • 学术资讯
  • Suppr Zotero 插件Zotero 插件
  • 邀请有礼
  • 套餐&价格
  • 历史记录
应用&插件
Suppr Zotero 插件Zotero 插件浏览器插件Mac 客户端Windows 客户端微信小程序
定价
高级版会员购买积分包购买API积分包
服务
文献检索文档翻译深度研究API 文档MCP 服务
关于我们
关于 Suppr公司介绍联系我们用户协议隐私条款
关注我们

Suppr 超能文献

核心技术专利:CN118964589B侵权必究
粤ICP备2023148730 号-1Suppr @ 2026

文献检索

告别复杂PubMed语法,用中文像聊天一样搜索,搜遍4000万医学文献。AI智能推荐,让科研检索更轻松。

立即免费搜索

文件翻译

保留排版,准确专业,支持PDF/Word/PPT等文件格式,支持 12+语言互译。

免费翻译文档

深度研究

AI帮你快速写综述,25分钟生成高质量综述,智能提取关键信息,辅助科研写作。

立即免费体验

相似文献

1
The cadherin-catenin adhesion system in signaling and cancer.信号传导与癌症中的钙黏蛋白-连环蛋白黏附系统
J Clin Invest. 2002 Apr;109(8):987-91. doi: 10.1172/JCI15429.
2
Rho-family GTPases in cadherin-mediated cell-cell adhesion.Rho家族小G蛋白在钙黏蛋白介导的细胞间黏附中的作用
Nat Rev Mol Cell Biol. 2001 Dec;2(12):887-97. doi: 10.1038/35103068.
3
[Dysfunction of cadherin cell adhesion system in cancer invasion and metastasis].[钙黏蛋白细胞黏附系统在癌症侵袭和转移中的功能障碍]
Gan To Kagaku Ryoho. 1999 Mar;26(4):565-71.
4
[Molecular mechanisms of early invasion of gastric cancer cells].[胃癌细胞早期侵袭的分子机制]
Nihon Rinsho. 2001 Apr;59 Suppl 4:81-7.
5
The integration of cell adhesion with gene expression: the role of beta-catenin.细胞黏附与基因表达的整合:β-连环蛋白的作用
Exp Cell Res. 2000 Nov 25;261(1):75-82. doi: 10.1006/excr.2000.5045.
6
Beta-catenin-mediated transactivation and cell-cell adhesion pathways are important in curcumin (diferuylmethane)-induced growth arrest and apoptosis in colon cancer cells.β-连环蛋白介导的转录激活和细胞间黏附途径在姜黄素(二阿魏酰甲烷)诱导结肠癌细胞生长停滞和凋亡过程中发挥重要作用。
Oncogene. 2002 Dec 5;21(55):8414-27. doi: 10.1038/sj.onc.1205947.
7
Beta-catenin interacts with low-molecular-weight protein tyrosine phosphatase leading to cadherin-mediated cell-cell adhesion increase.β-连环蛋白与低分子量蛋白酪氨酸磷酸酶相互作用,导致钙黏蛋白介导的细胞间黏附增加。
Cancer Res. 2002 Nov 15;62(22):6489-99.
8
Cadherin and catenin alterations in human cancer.人类癌症中的钙黏蛋白和连环蛋白改变
Genes Chromosomes Cancer. 2002 Jul;34(3):255-68. doi: 10.1002/gcc.10083.
9
Formin' adherens junctions.形成黏着连接。
Nat Cell Biol. 2004 Jan;6(1):12-4. doi: 10.1038/ncb0104-12.
10
Adherens junction proteins in tumour progression.肿瘤进展中的黏附连接蛋白。
Cancer Surv. 1995;24:129-40.

引用本文的文献

1
Beyond the Walls of Troy: A Scoping Review on Pharmacological Strategies to Enhance Drug Delivery Across the Blood-Brain Barrier and Blood-Tumor Barrier.超越特洛伊城墙:关于增强药物透过血脑屏障和血肿瘤屏障递送的药理学策略的范围综述
Int J Mol Sci. 2025 Jul 22;26(15):7050. doi: 10.3390/ijms26157050.
2
Antitumor Effect of Curcumin, D6 Turmeric, and Hydrochloride Mitoxantrone on Canine and Human Urothelial Cancer Cells.姜黄素、D6 姜黄和盐酸米托蒽醌对犬类和人类膀胱癌细胞的抗肿瘤作用。
Animals (Basel). 2025 May 29;15(11):1589. doi: 10.3390/ani15111589.
3
Calcium-dependent adhesion protein CDH18, a potential biomarker for prognosis in uterine corpus endometrial carcinoma.钙依赖性粘附蛋白CDH18,一种子宫体子宫内膜癌预后的潜在生物标志物。
Front Mol Biosci. 2025 Feb 13;12:1530253. doi: 10.3389/fmolb.2025.1530253. eCollection 2025.
4
Comparison of E-Cadherin Expression in Oral Verrucous Carcinoma and Normal Oral Mucosa: An Immunohistochemical Study.口腔疣状癌与正常口腔黏膜中E-钙黏蛋白表达的比较:一项免疫组织化学研究
Cureus. 2024 Nov 27;16(11):e74634. doi: 10.7759/cureus.74634. eCollection 2024 Nov.
5
Programmable protein degraders enable selective knockdown of pathogenic β-catenin subpopulations and .可编程蛋白降解剂能够选择性敲低致病性β-连环蛋白亚群。
bioRxiv. 2024 Nov 11:2024.11.10.622803. doi: 10.1101/2024.11.10.622803.
6
HIV1-Nef perturbs the integrity of blood testis barrier in rat model.HIV1-Nef破坏大鼠模型中血睾屏障的完整性。
Tissue Barriers. 2025 Jan 2;13(1):2357406. doi: 10.1080/21688370.2024.2357406. Epub 2024 May 22.
7
Mechanisms of the Wnt Pathways as a Potential Target Pathway in Atherosclerosis.Wnt信号通路作为动脉粥样硬化潜在靶通路的机制
J Lipid Atheroscler. 2023 Sep;12(3):223-236. doi: 10.12997/jla.2023.12.3.223. Epub 2023 Sep 7.
8
Epigallocatechin-3-Gallate, an Active Green Tea Component to Support Anti-VEGFA Therapy in Wet Age-Related Macular Degeneration.没食子酸表没食子儿茶素酯,一种支持湿性年龄相关性黄斑变性抗 VEGF 治疗的绿茶有效成分。
Nutrients. 2023 Jul 28;15(15):3358. doi: 10.3390/nu15153358.
9
Immunohistochemical Expression of E-Cadherin and β-Catenin in Oral Squamous Cell Carcinoma.E-钙黏蛋白和β-连环蛋白在口腔鳞状细胞癌中的免疫组化表达
J West Afr Coll Surg. 2023 Jul-Sep;13(3):43-47. doi: 10.4103/jwas.jwas_1_23. Epub 2023 Jun 27.
10
CDH4 inhibits ferroptosis in oral squamous cell carcinoma cells.CDH4 抑制口腔鳞状细胞癌细胞中的铁死亡。
BMC Oral Health. 2023 May 27;23(1):329. doi: 10.1186/s12903-023-03046-3.

本文引用的文献

1
Rho-family GTPases in cadherin-mediated cell-cell adhesion.Rho家族小G蛋白在钙黏蛋白介导的细胞间黏附中的作用
Nat Rev Mol Cell Biol. 2001 Dec;2(12):887-97. doi: 10.1038/35103068.
2
Rho family proteins: coordinating cell responses.Rho家族蛋白:协调细胞反应。
Trends Cell Biol. 2001 Dec;11(12):471-7. doi: 10.1016/s0962-8924(01)02153-5.
3
Leaving the neighborhood: molecular mechanisms involved during epithelial-mesenchymal transition.离开邻域:上皮-间质转化过程中涉及的分子机制。
Bioessays. 2001 Oct;23(10):912-23. doi: 10.1002/bies.1132.
4
Down-regulation of beta-catenin by activated p53.激活的p53对β-连环蛋白的下调作用。
Mol Cell Biol. 2001 Oct;21(20):6768-81. doi: 10.1128/MCB.21.20.6768-6781.2001.
5
E-cadherin regulates cell growth by modulating proliferation-dependent beta-catenin transcriptional activity.E-钙黏蛋白通过调节依赖增殖的β-连环蛋白转录活性来调控细胞生长。
J Cell Biol. 2001 Sep 17;154(6):1185-96. doi: 10.1083/jcb.200104036.
6
Molecular architecture of adherens junctions.黏着连接的分子结构
Curr Opin Cell Biol. 2001 Oct;13(5):600-3. doi: 10.1016/s0955-0674(00)00257-x.
7
Deregulated beta-catenin induces a p53- and ARF-dependent growth arrest and cooperates with Ras in transformation.失调的β-连环蛋白诱导p53和ARF依赖性生长停滞,并在转化过程中与Ras协同作用。
EMBO J. 2001 Sep 3;20(17):4912-22. doi: 10.1093/emboj/20.17.4912.
8
Variable beta-catenin expression in colorectal cancers indicates tumor progression driven by the tumor environment.结直肠癌中β-连环蛋白表达的变化表明肿瘤进展是由肿瘤环境驱动的。
Proc Natl Acad Sci U S A. 2001 Aug 28;98(18):10356-61. doi: 10.1073/pnas.171610498.
9
Vitamin D(3) promotes the differentiation of colon carcinoma cells by the induction of E-cadherin and the inhibition of beta-catenin signaling.维生素D(3) 通过诱导E-钙黏蛋白和抑制β-连环蛋白信号传导来促进结肠癌细胞的分化。
J Cell Biol. 2001 Jul 23;154(2):369-87. doi: 10.1083/jcb.200102028.
10
The two-handed E box binding zinc finger protein SIP1 downregulates E-cadherin and induces invasion.双手E盒结合锌指蛋白SIP1下调E-钙黏蛋白并诱导侵袭。
Mol Cell. 2001 Jun;7(6):1267-78. doi: 10.1016/s1097-2765(01)00260-x.

The cadherin-catenin adhesion system in signaling and cancer.

作者信息

Conacci-Sorrell Maralice, Zhurinsky Jacob, Ben-Ze'ev Avri

机构信息

Department of Molecular Cell Biology, The Weizmann Institute of Science, Rehovot 76100, Israel.

出版信息

J Clin Invest. 2002 Apr;109(8):987-91. doi: 10.1172/JCI15429.

DOI:10.1172/JCI15429
PMID:11956233
原文链接:https://pmc.ncbi.nlm.nih.gov/articles/PMC150951/
Abstract
摘要