Krey H
Klin Monbl Augenheilkd. 1975 Aug;167(2):295-301.
A study of the choroidal vascular system in post-mortem eyes with negative histories of ocular and systemic vascular disease showed that there are progressive capillary changes with increasing age. The investigation was limited to the equatorial and peripheral choriocapillaries. Capillary changes and a patchy vascular atrophy of the capillary layer with increasing width of the intercapillary connective tissue were observed to start in the area of the ora serrata. Atrophic changes were most commonly located in the temporal zones. In contrast to the senescent changes of the capillaries, involvement of the arterioles was relatively mild; complete obliteration of an arteriole has not been observed even in atrophic capillary zones. Causal relationships of senile capillary changes could not be ascertained on a pure morphological basis. Clinical relevance has been discussed.
一项针对眼部和全身血管疾病病史均为阴性的死后眼睛脉络膜血管系统的研究表明,随着年龄的增长,毛细血管会发生渐进性变化。该研究仅限于赤道和周边脉络膜毛细血管。观察到在锯齿缘区域开始出现毛细血管变化以及毛细血管层的斑片状血管萎缩,同时毛细血管间结缔组织宽度增加。萎缩性变化最常见于颞侧区域。与毛细血管的衰老变化不同,小动脉的受累相对较轻;即使在萎缩的毛细血管区域,也未观察到小动脉完全闭塞的情况。仅基于纯粹的形态学基础无法确定老年毛细血管变化的因果关系。文中已讨论了其临床相关性。