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帕金森病入门指南。

Parkinson's disease primer.

作者信息

Miller Judith L

机构信息

Evercare, Minneapolis, MN, USA.

出版信息

Geriatr Nurs. 2002 Mar-Apr;23(2):69-74; quiz 75. doi: 10.1067/mgn.2002.123789.

Abstract

Parkinson's disease (PD) is a progressive, neurodegenerative disorder characterized by the primary motor symptoms of bradykinesia, muscle rigidity, resting tremor, and postural instability. PD most often affects people older than 65, although it does occur at younger ages. The purpose of this article is to provide a brief overview of the pathophysiology of PD and a review of current literature, assessment and diagnostic techniques, therapeutic interventions, and management protocols. Treatment goals are twofold: short-term treatment to alleviate symptoms and reverse functional disability and long-term treatment to maintain effectiveness and limit pharmacologic complications.

摘要

帕金森病(PD)是一种进行性神经退行性疾病,其主要运动症状包括运动迟缓、肌肉僵硬、静止性震颤和姿势不稳。PD最常影响65岁以上的人群,不过也会在较年轻的年龄段出现。本文旨在简要概述PD的病理生理学,并综述当前的文献、评估和诊断技术、治疗干预措施及管理方案。治疗目标有两个:短期治疗以缓解症状并逆转功能残疾,长期治疗以维持疗效并限制药物并发症。

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