Strimlan C V, Dines D E, Payne W S
Mayo Clin Proc. 1975 Dec;50(12):702-5.
In a group of 47 patients with mediastinal granulomas, the most common clinical symptoms were cough, chest pain, dysphagia, hemoptysis, and dyspnea. The main laboratory findings were right paratracheal or hilar mass on chest roentgenogram, positive histoplasmin skin test, and caseating granuloma on histopathologic examination. Complications included fibrosing mediastinitis with superior vena cava obstruction, esophageal compression, and major upper airway compression. Treatment was usually surgical resection or evacuation of caseous contents. The prognosis in most patients with mediastinal granulomas appears to be good--long-term survival with minimal or no disability.
在一组47例纵隔肉芽肿患者中,最常见的临床症状为咳嗽、胸痛、吞咽困难、咯血和呼吸困难。主要实验室检查结果为胸部X线片显示右气管旁或肺门肿块、组织胞浆菌素皮肤试验阳性以及组织病理学检查显示干酪样肉芽肿。并发症包括伴有上腔静脉梗阻、食管受压和主要上气道受压的纤维性纵隔炎。治疗通常为手术切除或清除干酪样内容物。大多数纵隔肉芽肿患者的预后似乎良好——可长期存活且致残率极低或无致残。