Zayfert Claudia, Dums Aricca R, Ferguson Robert J, Hegel Mark T
Department of Psychiatry, Dartmouth Medical School, Lebanon, New Hampshire 03756, USA.
J Nerv Ment Dis. 2002 Apr;190(4):233-40. doi: 10.1097/00005053-200204000-00004.
Although anxiety disorders have been associated with impairments in self-reported health functioning, the relative effect of various anxiety disorders has not been studied. We compared health functioning of patients with a principal diagnosis of posttraumatic stress disorder (PTSD), panic disorder (PD), generalized anxiety disorder (GAD), and major depressive disorder (MDD). Patients with PTSD and MDD were equally impaired on overall mental health functioning, and both were significantly worse than patients with PD and GAD. PTSD was associated with significantly worse physical health functioning relative to PD, GAD, and MDD. Hierarchical regression showed that the association of PTSD with physical health functioning was unique and was not caused by the effects of age, depression, or comorbid anxiety disorders. Both PTSD and comorbid anxiety accounted for unique variance in mental functioning. These results highlight the association of PTSD with impaired physical and mental functioning and suggest that effective treatment of PTSD may affect overall health.
尽管焦虑症与自我报告的健康功能受损有关，但尚未对各种焦虑症的相对影响进行研究。我们比较了主要诊断为创伤后应激障碍（PTSD）、惊恐障碍（PD）、广泛性焦虑症（GAD）和重度抑郁症（MDD）患者的健康功能。PTSD和MDD患者在整体心理健康功能方面同样受损，且两者均显著差于PD和GAD患者。与PD、GAD和MDD相比，PTSD与显著更差的身体健康功能相关。分层回归显示，PTSD与身体健康功能之间的关联是独特的，并非由年龄、抑郁或共病焦虑症的影响所致。PTSD和共病焦虑症均在心理功能方面占独特的方差。这些结果突出了PTSD与身心功能受损之间的关联，并表明有效治疗PTSD可能会影响整体健康。
