Kim Jae-Han, Kim Shin-Woo, Kang Hye-Ryun, Bae Gi-Bum, Park Jee-Hyun, Nam Eon-Jeong, Kang Young-Mo, Lee Jong-Myung, Kim Nung-Soo
Department of Internal Medicine, School of Medicine, Kyungpook National University, Daegu, Korea.
J Korean Med Sci. 2002 Apr;17(2):263-5. doi: 10.3346/jkms.2002.17.2.263.
Stenotrophomonas maltophilia (previously named Xanthomonas maltophilia) is an aerobic, non-fermentive, Gram-negative bacillus that is wide spread in the environment. It was considered to be an organism with limited pathogenic potential, which was rarely capable of causing diseases in human other than those who were in debilitated or immunocompromised state. More recent studies have established that Stenotrophomonas maltophilia can behave as a true pathogen. Endocarditis due to this organism is rare, and only 24 cases of Stenotrophomonas maltophilia endocarditis have been reported in the medical literature. Most cases were associated with risk factors, including intravenous drug abuse, dental treatment, infected intravenous devices, and previous cardiac surgery. We present a case with two episodes of Stenotrophomonas maltophilia endocarditis after mitral valve prosthesis implantation, which was treated with antibiotics initially, and a combination of antibiotics and surgery later. To our knowledge, this is the first case of repetitive endocarditis due to Stenotrophomonas maltophilia.
嗜麦芽窄食单胞菌（以前称为嗜麦芽黄单胞菌）是一种需氧、不发酵、革兰氏阴性杆菌，广泛存在于环境中。它曾被认为是一种致病潜力有限的微生物，除了身体虚弱或免疫功能低下的人外，很少能在人类中引起疾病。最近的研究表明，嗜麦芽窄食单胞菌可表现为真正的病原体。由该微生物引起的心内膜炎很少见，医学文献中仅报道了24例嗜麦芽窄食单胞菌心内膜炎病例。大多数病例与危险因素有关，包括静脉药物滥用、牙科治疗、感染的静脉装置和既往心脏手术。我们报告一例二尖瓣人工瓣膜植入术后发生两次嗜麦芽窄食单胞菌心内膜炎的病例，最初用抗生素治疗，后来采用抗生素与手术联合治疗。据我们所知，这是首例由嗜麦芽窄食单胞菌引起的复发性心内膜炎病例。
