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嗜麦芽窄食单胞菌:脑膜炎的罕见病因。

Stenotrophomonas maltophilia: rare cause of meningitis.

作者信息

Correia Cátia Rodrigues, Ferreira Sara Tavares, Nunes Paula

机构信息

Department of Pediatrics, São Francisco Xavier Hospital, Lisbon, Portugal.

出版信息

Pediatr Int. 2014 Aug;56(4):e21-2. doi: 10.1111/ped.12352.

DOI:10.1111/ped.12352
PMID:25252064
Abstract

Stenotrophomonas maltophilia is a Gram-negative bacillus, which is an extremely rare cause of meningitis. To our knowledge, there are only five previous pediatrics cases. Here, we describe the case of a 4-year-old boy who developed meningitis associated with this organism, after several neurosurgical procedures and previous treatment with a broad-spectrum antibiotic. He was treated successfully with a combination of trimethoprim-sulfamethoxazole, ceftazidime and levofloxacin. Stenotrophomonas maltophilia should be considered as a potential cause of meningitis, especially among severely debilitated or immunosuppressed patients. Antimicrobial therapy is complicated by the high resistance of the organism to multiple antibiotics.

摘要

嗜麦芽窄食单胞菌是一种革兰氏阴性杆菌,是极为罕见的脑膜炎病因。据我们所知,此前仅有5例儿科病例。在此,我们描述一名4岁男孩的病例,该男孩在经历多次神经外科手术后,曾接受广谱抗生素治疗,之后发生了与该病菌相关的脑膜炎。他通过复方新诺明、头孢他啶和左氧氟沙星联合治疗而康复。嗜麦芽窄食单胞菌应被视为脑膜炎的潜在病因,尤其是在严重虚弱或免疫抑制的患者中。由于该病菌对多种抗生素具有高度耐药性,抗菌治疗变得复杂。

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