Al-Inany Hesham, Youssef Gamal, Abd ElMaguid Ahmed, Abdel Hamid Moustapha, Naguib Ahmed
Department of Obstetrics and Gynecology, Cairo University, Cairo, Egypt.
Gynecol Obstet Invest. 2002;53(2):75-8. doi: 10.1159/000052996.
To determine whether closed subcutaneous drainage systems were efficacious in reducing the rate of wound breakdown of Pfannenstiel incision after cesarean section (CS) in obese females.
Prospective controlled clinical trial.
118 obese pregnant females with a body mass index >32 undergoing CS were divided into two groups: group I (n = 78) with closed subcutaneous drainage system and group II (n = 40) without drainage system. Incision closure technique was standardized. Prophylactic antibiotics were given routinely to both groups.
Primary outcomes were the incidence of wound breakdown in both groups together with rate of hematoma formation and occurrence of fever. Secondary outcomes were amount of fluid drained, need for redressing.
Wound breakdown occurred in 9 cases in group I (11.5%), while it happened in 5 cases in group II (12.5%) (p > 0.05). Relative risk was 0.92 (95% CI 0.26-3.75). Hematoma formation was observed in only 1 case in the nondrainage group (group II). Fever was observed in 18 cases in group I (23.1%) in the first 24 h postoperative while in group II, 13 cases developed fever (32.5%) (p > 0.05). The need for redressing within the first 24 h was only in 2.5% of cases in group I while it was 17.9% in group II (p < 0.05).
We found no significant benefit in using a subcutaneous drain as a prophylactic measure against wound breakdown in obese pregnant females undergoing CS as long as they received a prophylactic antibiotic.
确定封闭式皮下引流系统对于降低肥胖女性剖宫产术后Pfannenstiel切口伤口裂开率是否有效。
前瞻性对照临床试验。
118例体重指数>32的肥胖孕妇行剖宫产术,分为两组:I组(n = 78)采用封闭式皮下引流系统,II组(n = 40)不采用引流系统。切口缝合技术标准化。两组均常规给予预防性抗生素。
主要指标为两组伤口裂开的发生率、血肿形成率及发热情况。次要指标为引流量、换药需求。
I组9例(11.5%)发生伤口裂开,II组5例(12.5%)发生伤口裂开(p>0.05)。相对危险度为0.92(95%CI 0.26 - 3.75)。非引流组(II组)仅1例观察到血肿形成。I组18例(23.1%)术后24小时内发热,II组13例(32.5%)发热(p>0.05)。I组术后24小时内仅2.5%的病例需要换药,II组为17.9%(p<0.05)。
我们发现,对于行剖宫产术的肥胖孕妇,只要接受了预防性抗生素治疗,使用皮下引流作为预防伤口裂开的措施并无显著益处。