Barreda Bolaños Fernando, Sánchez Lihon Juvenal, Misad Nuñez Oscar, Combe Gutiérrez Juan, Amorín Kajatt Edgar, Rojas Gonzáles Víctor, Celis Zapata Juan, Díaz Del Olmo García Mauricio
Servicio de Gastroenterologia del Departamento de Abdomen del Insituto de Enfermedades Neoplasicas.
Rev Gastroenterol Peru. 2002 Jan-Mar;22(1):45-68.
The first part of this report reviews the definition, history and clinical aspects of Barrett s Esophagus. The next section explains the results obtained at INEN, Lima Peru. The first case of Barrett s Esophagus complicated with Adenocarcinoma was diagnosed in 1956. The prevalence of Barrett s Esophagus in 3,904 patients who were administered endoscopy examinations is 0.64%. The evaluation of 40 patients with Barrett s Esophagus indicated that it has a greater incidence in males than in females (3:1). The average age of patients with Barrett s Esophagus is 60 years and its incidence increases as they grow older. It manifests itself in 40 year old persons and is specially strong from 55 to 64 years of age. Dysplasia is associated with Intestinal Metaplasia. The frequency of the epidermoid carcinoma is of 96% and for adenocarcinoma of 4% in the period of evaluation of 15 years (1985-1999). There is no difference in the tendency of epidermoid carcinoma and esophagus adenocarcinoma during the same evaluation period. The incidence of Barrett s Esophagus adenocarcinoma is higher in males than in females: (6:1). Intestinal metaplasia is found in 13/14 patients evaluated in relation to the esophagus adenocarcinoma. Long segment Barrett s Esophagus, is found in 13/14 patients complicated with adenocarcinoma. The average size of the long segment Barrett s Esophagus is of 6 cm in the patients with adenocarcinoma.
本报告的第一部分回顾了巴雷特食管的定义、历史和临床方面。下一部分解释了在秘鲁利马的秘鲁国立核能源研究所（INEN）所取得的结果。1956年诊断出首例并发腺癌的巴雷特食管病例。在接受内镜检查的3904名患者中，巴雷特食管的患病率为0.64%。对40例巴雷特食管患者的评估表明，男性的发病率高于女性（3:1）。巴雷特食管患者的平均年龄为60岁，且发病率随年龄增长而增加。它在40岁的人群中出现，在55至64岁时尤为明显。发育异常与肠化生相关。在15年（1985 - 1999年）的评估期内，表皮样癌的发生率为96%，腺癌为4%。在同一评估期内，表皮样癌和食管腺癌的发病趋势没有差异。巴雷特食管腺癌的发病率男性高于女性：（6:1）。在与食管腺癌相关的14例接受评估的患者中，有13例发现了肠化生。在14例并发腺癌的患者中，有13例发现了长段巴雷特食管。腺癌患者中长段巴雷特食管的平均长度为6厘米。
