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[肝细胞癌相关的红细胞增多症。两例报告]

[Erythrocytosis associated with hepatocellular carcinoma. Two case reports].

作者信息

Argumanis Enrique, Quispe Dolly, Ruiz Eloy

机构信息

Medico Hematologo, Instituto de Enfermedades Neoplasicas.

出版信息

Rev Gastroenterol Peru. 2002 Jan-Mar;22(1):84-7.

Abstract

Erythrocytosis is a well-known paraneoplastic syndrome of hepatocellular carcinoma (HCC), occurring in 1% of cases of this neoplasm. This report describes two HCC patients who manifested erythrocytosis in their clinical report. Similar features found in both patients were a large tumour burden, high concentration of hemoglobin and hematocrit, increased levels of serum alphafetoprotein (AFP) and positive HBsAg. Right lobectomy of the liver was performed. Histological findings of the specimen showed HCC of trabecular pattern. Hemoglobin and hematocrit returned to normal range after the operation.

摘要

红细胞增多症是一种众所周知的肝细胞癌(HCC)副肿瘤综合征,在该肿瘤病例中发生率为1%。本报告描述了两名在临床报告中表现出红细胞增多症的HCC患者。两名患者的相似特征为肿瘤负荷大、血红蛋白和血细胞比容浓度高、血清甲胎蛋白(AFP)水平升高以及乙肝表面抗原(HBsAg)阳性。对肝脏进行了右叶切除术。标本的组织学检查结果显示为小梁状模式的HCC。术后血红蛋白和血细胞比容恢复到正常范围。

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