Scaffidi L
Minerva Med. 1975 Dec 12;66(85):4569-74.
Data relating to three statistical, clinical and epidemiological research projects covering a total of 350 cases of peripheral obliterating arteriopathy, collected by the same group from different Sicilian provinces and based on the same classification, are presented. Athersclerosis was a prominent feature (50% in the eastern provinces, 60% in the west), especially in the 6th decade of life. Diabetes, alone or in association with athersclerosis, was also more common in the west (18%) as opposed to the east (5--%). Burger's disease was noted in 3% and infection in 8% (presumably viral on 3.5%). Comparison is made with the national statistics produced by Corsi and the partial results of other Sicilian workers. The clinical data showed: a) the disease appeared at least 10 years earlier in subjects with athersclerosis and diabetes; 2) these subjects was also more exposed to the risk of coronary and cereabral involvement; c) asymptomatic forms were observable in 8% of atherosclerotics and 20% of those with both diabetes and athersclerosis. Reasons for the increase of degenerative forms throughout the world are discussed. Correct, systematic examination for the detection of forms with few or no symptoms is definitely required.
本文展示了与三个统计、临床和流行病学研究项目相关的数据，这些项目共涵盖350例周围闭塞性动脉病病例，由同一研究团队从西西里岛不同省份收集，且基于相同分类。动脉粥样硬化是一个突出特征（东部省份占50%，西部占60%），尤其在60岁年龄段。糖尿病单独出现或与动脉粥样硬化并存时，在西部也更为常见（18%），而东部为5%。血栓闭塞性脉管炎占3%，感染占8%（推测3.5%为病毒感染）。文中将这些数据与科尔西编制的全国统计数据以及其他西西里岛研究人员的部分结果进行了比较。临床数据显示：a）动脉粥样硬化和糖尿病患者发病时间至少提前10年；b）这些患者也更容易出现冠状动脉和脑部受累风险；c）8%的动脉粥样硬化患者以及20%同时患有糖尿病和动脉粥样硬化的患者存在无症状形式。文中讨论了世界各地退行性疾病形式增加的原因。明确需要进行正确、系统的检查以检测出症状轻微或无症状的病例。
