Raphael Kalani, Tokeshi Jinichi
University of Hawaii, John A. Burns School of Medicine, USA.
Hawaii Med J. 2002 Mar;61(3):46-7.
The syndrome of inappropriate antidiuretic hormone secretion (SIADH) is a rare but serious adverse effect of the selective serotonin reuptake inhibitors (SSRIs). Although many case reports describe this association, few report the effect of rechallenge with another SSRI. We present a case of an elderly patient who developed hyponatremia with sertraline and SIADH when rechallenged with fluoxetine.
抗利尿激素分泌异常综合征（SIADH）是选择性5-羟色胺再摄取抑制剂（SSRIs）罕见但严重的不良反应。尽管许多病例报告描述了这种关联，但很少有报告再次使用另一种SSRI的影响。我们报告一例老年患者，再次使用氟西汀时出现血清素和SIADH导致的低钠血症。
