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[氯胺酮——梦想与现实]

[Ketamine--dreams and realities].

作者信息

Arditti J, Spadari M, de Haro L, Brun A, Bourdon J H, Valli M

机构信息

Hôpital Salvator, Laboratoire de Toxicologie-Centre antipoison 249 boulevard de Sainte Marguerite-13009 Marseille.

出版信息

Acta Clin Belg. 2002;57 Suppl 1:31-3.

PMID:11974440
Abstract

Ketamine is an anaesthetic used in human medicine and veterinary practice, synthesised on 1962 and marketed on 1970 in France. Recreational uses were described during 1992 in the medical community and in 1996 in the dance settings. The chemical name of ketamine is 2--(2chlorophenyl)2-(methylamine)-cyclohexanone, an aryl cyclohexylamine, structurally related to phencyclidine. Ketamine is known under the following street names: Keta K, Kate, Special K, Vitamin K, la Golden, la Vétérinaire. Ketamine is used intranasally, orally and intramusculary in recreational use. Ketamine is manufactured by the chemical industry. Due to the complicated synthesis, it is sold illicitly for recreational use. Ketamine is a dissociative drug, and the user enters in a psychedelic dream with hallucinations, floating sensation, feeling of dissociation of the mind from the body. The dream is forgotten, the user full in reality with loss of self control, risk of acute intoxication. In long-term exposure, tolerance, dependence, withdrawal signs and flash back are described. Ketamine trademarks are subject to control in France through medicine legislation Ketamine and its salts are subject to control under the national legislation on narcotics and psychotropics substance. From September 2001, the theft of medical and veterinary trademarks have to be declared to police, care health authority Pharmacy control authority and French Health Products Safety Agency.

摘要

氯胺酮是一种用于人类医学和兽医实践的麻醉剂,于1962年合成,并于1970年在法国上市。1992年在医学界以及1996年在舞蹈场所出现了其被用于娱乐的情况。氯胺酮的化学名称是2-(2-氯苯基)-2-(甲胺基)环己酮,一种芳基环己胺,在结构上与苯环己哌啶相关。氯胺酮有以下一些街头名称:Keta K、Kate、Special K、维生素K、la Golden、la Vétérinaire。氯胺酮在娱乐用途中通过鼻内、口服和肌肉注射使用。氯胺酮由化学工业生产。由于其合成复杂,它被非法出售用于娱乐。氯胺酮是一种分离性药物,使用者会进入一个伴有幻觉、漂浮感、身心分离感的迷幻梦境。这个梦境会被遗忘,使用者回到现实中时会失去自我控制能力,有急性中毒的风险。长期接触氯胺酮会出现耐受性、依赖性、戒断症状和闪回现象。在法国,氯胺酮的商标受药品立法管控。氯胺酮及其盐类受国家关于麻醉药品和精神药物的立法管控。自2001年9月起,医疗和兽医商标被盗必须向警方、卫生保健当局、药房监管当局和法国健康产品安全局申报。

相似文献

1
[Ketamine--dreams and realities].[氯胺酮——梦想与现实]
Acta Clin Belg. 2002;57 Suppl 1:31-3.
2
Ketamine - reves et realites.氯胺酮——苏醒与现实。
Acta Clin Belg. 2002;57 Suppl 1:31-3. doi: 10.1179/acb.2002.073.
3
Ketamine : from medicine to misuse.氯胺酮:从医学用途到滥用
CNS Drugs. 2006;20(3):199-218. doi: 10.2165/00023210-200620030-00003.
4
Ketamine as a street drug.氯胺酮作为一种街头毒品。
Emerg Med Serv. 2001 Nov;30(11):30, 32, 34 passim.
5
[Psychedelic effects of subanesthetic doses of ketamine].[亚麻醉剂量氯胺酮的致幻作用]
Zhongguo Yi Xue Ke Xue Yuan Xue Bao. 2009 Feb;31(1):68-72.
6
Effects of ketamine on psychomotor, sensory and cognitive functions relevant for driving ability.氯胺酮对与驾驶能力相关的精神运动、感觉和认知功能的影响。
Forensic Sci Int. 2015 Jul;252:127-42. doi: 10.1016/j.forsciint.2015.04.024. Epub 2015 Apr 27.
7
Ketamine dependence.氯胺酮依赖
Anaesth Intensive Care. 2002 Jun;30(3):382-4. doi: 10.1177/0310057X0203000323.
8
[New drugs at "rave parties": ketamine and prolintane].["狂欢派对上的新型毒品:氯胺酮和普罗林坦"]
Acta Clin Belg. 2002;57 Suppl 1:41-6.
9
Paliperidone for the treatment of ketamine-induced psychosis: a case report.帕利哌酮治疗氯胺酮诱导的精神病:病例报告。
Int J Psychiatry Med. 2014;48(2):103-8. doi: 10.2190/PM.48.2.c.
10
Ketamine for procedural sedation and analgesia in pediatric emergency medicine: a UK perspective.氯胺酮用于儿科急诊医学中的程序性镇静和镇痛:英国视角
Paediatr Anaesth. 2008 Jan;18(1):25-9. doi: 10.1111/j.1460-9592.2007.02395.x.

引用本文的文献

1
The Special K Constellation, a Rare Presentation of Ketamine Use: A Case Report.“特别K”星座:氯胺酮使用的罕见表现——病例报告
Cureus. 2019 May 28;11(5):e4766. doi: 10.7759/cureus.4766.
2
Ketamine and Ketamine Metabolite Pharmacology: Insights into Therapeutic Mechanisms.氯胺酮及其代谢产物的药理学:治疗机制的新视角。
Pharmacol Rev. 2018 Jul;70(3):621-660. doi: 10.1124/pr.117.015198.
3
Ketamine : from medicine to misuse.氯胺酮:从医学用途到滥用
CNS Drugs. 2006;20(3):199-218. doi: 10.2165/00023210-200620030-00003.