Ketamine as a street drug.

The excellent safety profile of ketamine has made it the drug of choice for both pediatric sedation and much veterinary medicine. Fortunately, this safety record also means that few patients who deliberately overdose during recreational use will have substantial morbidity or mortality. Most morbidity and mortality will occur from accidents during the induced dysphoric state. Since vomiting occurs with high doses, aspiration is a distinct possibility in the deeply comatose patient.