Molecular mechanisms of neutrophil recruitment elicited by bacteria in the lungs.

The recruitment of leukocytes to an extravascular destination requires intercellular communication between tissue cells and leukocytes. The molecules mediating this intercellular communication play differing roles in recruiting different types of leukocytes, in response to different stimuli, in different tissues, and in different hosts. The present communication reviews the adhesion molecules, chemokines, other cytokines, and NF- kappa B proteins which regulate the recruitment of neutrophils elicited by bacteria in the lungs.