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伴有淋巴结及肺转移的毛母质癌:一例发生于膝部的病例报告

Pilomatrix carcinoma with lymph node and pulmonary metastasis: report of a case arising on the knee.

作者信息

De Gálvez-Aranda Maria Victoria, Herrera-Ceballos Enrique, Sánchez-Sánchez Purificación, Bosch-García Ricardo Juan, Matilla-Vicente Alfredo

机构信息

Dermatology Service, Faculty of Medicine, Virgen de la Victoria University Hospital, Malaga, Spain.

出版信息

Am J Dermatopathol. 2002 Apr;24(2):139-43. doi: 10.1097/00000372-200204000-00006.

DOI:10.1097/00000372-200204000-00006
PMID:11979074
Abstract

A 58-year-old woman presented with a pilomatrix carcinoma on the right knee. The tumor developed at the site of a previous lesion that had been present since she was 30 years old. Histologic study showed the presence of basaloid cells with numerous atypical mitoses, shadow cells, and calcification. After several surgical excisions, the tumor mass infiltrated the subcutaneous tissue, muscle, and bone, resulting in inguinal lymph node and pulmonary metastasis. We also review the literature and comment on the histopathologic differences from other cutaneous tumors.

摘要

一名58岁女性患者右膝出现毛母质癌。肿瘤发生于她30岁起就存在的先前病变部位。组织学研究显示存在具有大量非典型有丝分裂的基底样细胞、影细胞和钙化。经过多次手术切除后,肿瘤肿块浸润至皮下组织、肌肉和骨骼,导致腹股沟淋巴结和肺转移。我们还回顾了文献,并对与其他皮肤肿瘤的组织病理学差异进行了评论。

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