Olcén P, Kjellander J, Danielsson D, Lindquist B L
J Clin Pathol. 1979 Dec;32(12):1222-5. doi: 10.1136/jcp.32.12.1222.
Different specimens and techniques have been used in the diagnosis of carriers of Neisseria meningitidis, reflecting the uncertainty about the optimal diagnostic procedure. In the present investigation the culture yield of meningococci from throat specimens was compared to that from nasopharyngeal speimens in 178 persons: 44 carriers were diagnosed. All of them were detected by culture of throat specimens while 34% of them would have remained undiagnosed if only nasopharyngeal specimens had been examined. Storage of throat specimens in a transport medium for 24 hours before culture gave a negative culture for meningococci in 41% of the carriers. This loss was surprisingly high, the reasons for which are discussed.
在脑膜炎奈瑟菌携带者的诊断中,人们使用了不同的标本和技术,这反映出最佳诊断程序尚存在不确定性。在本次调查中,对178人的咽喉标本和鼻咽标本中脑膜炎球菌的培养产量进行了比较:确诊了44名携带者。所有携带者均通过咽喉标本培养检测出来,而如果仅检查鼻咽标本,其中34%的携带者将无法被诊断出来。咽喉标本在运送培养基中保存24小时后再进行培养,41%的携带者脑膜炎球菌培养结果呈阴性。这种损失出奇地高,文中对其原因进行了讨论。