KELLOGG D S, PEACOCK W L, DEACON W E, BROWN L, PIRKLE D I
J Bacteriol. 1963 Jun;85(6):1274-9. doi: 10.1128/jb.85.6.1274-1279.1963.
Kellogg, Douglas S., Jr. (Communicable Disease Center, Atlanta, Ga.), William L. Peacock, Jr., W. E. Deacon, L. Brown, and Carl I. Pirkle. Neisseria gonorrhoeae. I. Virulence genetically linked to clonal variation. J. Bacteriol. 85:1274-1279. 1963.-One type, obtained from the purulent exudate of acute gonorrhea was maintained by 69 selective in vitro passages, at which point the organisms produced infections in human volunteers. A predominance of clonal types found in laboratory strains and a lack of ability to infect human volunteers resulted from 69 nonselective in vitro passages. Physiological and serological characteristics of the clonal types are compared. We are now in a position to study Neisseria gonorrhoeae organisms in their virulent form.
小凯洛格，道格拉斯·S.（佐治亚州亚特兰大传染病中心），小威廉·L.皮科克，W.E.迪肯，L.布朗，以及卡尔·I.皮尔克尔。淋病奈瑟菌。I. 毒力与克隆变异存在遗传关联。《细菌学杂志》85:1274 - 1279。1963年。——从急性淋病的脓性渗出物中获取的一种菌株，经69次体外选择性传代得以维持，此时该菌株可使人类志愿者感染。经69次非选择性体外传代后，实验室菌株中克隆类型占优势且丧失了感染人类志愿者的能力。对克隆类型的生理和血清学特征进行了比较。我们现在能够研究具有毒力形式的淋病奈瑟菌。
