Kanai H, Yamada K, Aihara N, Watanabe K
Department of Neurosurgery, Kakegawa City General Hospital, Kakegawa, Shizuoka.
Neurol Med Chir (Tokyo). 2000 May;40(5):283-6. doi: 10.2176/nmc.40.283.
A 48-year-old female presented with headache and limitation of upward gaze. She had a history of total gastrectomy for gastric adenocarcinoma 2 years previously. Computed tomography with contrast medium and T1-weighted magnetic resonance (MR) imaging with gadolinium showed ring-like enhancement of a solitary mass in the pineal region with obstructive hydrocephalus. T2-weighted MR imaging showed the tumor as hypointense. This MR imaging finding complicated the preoperative diagnosis, but malignancy was suspected from the medical history. The tumor was subtotally resected via the occipital transtentorial approach with a rigid endoscope. Histological examination of the surgical specimen revealed adenocarcinoma cells with extensive coagulation necrosis, which might have contributed to the hypointensity on T2-weighted MR imaging. Correct diagnosis of metastatic adenocarcinoma based only on MR imaging may be difficult in such cases, but metastatic adenocarcinoma of the pineal region must be considered in the differential diagnosis of pineal tumors.
一名48岁女性因头痛及向上凝视受限就诊。她两年前因胃腺癌接受了全胃切除术。增强计算机断层扫描及钆剂增强T1加权磁共振成像显示松果体区有一孤立肿块呈环状强化,伴有梗阻性脑积水。T2加权磁共振成像显示肿瘤呈低信号。这种磁共振成像表现使术前诊断复杂化,但根据病史怀疑为恶性肿瘤。通过枕下经小脑幕入路并使用硬式内镜对肿瘤进行了次全切除。手术标本的组织学检查显示腺癌细胞伴有广泛的凝固性坏死,这可能是T2加权磁共振成像上低信号的原因。在此类病例中,仅基于磁共振成像正确诊断转移性腺癌可能困难,但在松果体区肿瘤的鉴别诊断中必须考虑松果体区转移性腺癌。