Nikitin Iu P, Kuznetsov A A, Maliutina S K
Ter Arkh. 2002;74(3):72-5.
To study the relationship between clinical values of a standard epidemiological study of a male population and the length and variability of Q-T and R-R intervals.
A representative sampling from a male population (2184 subjects aged 25-64 years) in Novosibirsk was examined using standard epidemiological methods. Later 251 men were excluded from the study because of impossibility of correct analysis of ECG. The length and dispersion of Q-T interval and time parameters of variability of R-R interval were evaluated.
The size and variability of Q-T and R-R intervals are associated with age and AP irrespective of other clinical parameters of a simultaneous epidemiological study. The length of R-R interval is independently related to body weight index, tobacco smoking, and plasma triglyceride level. R-R variability parameters are associated with coronary disease irrespective of the risk factors.
Scanning studies with complex analysis of Q-T and R-R interval duration and variability effectively detect subjects at a high risk of arrhythmias and fatal events.
研究男性人群标准流行病学研究的临床指标与Q-T间期及R-R间期的长度和变异性之间的关系。
采用标准流行病学方法对新西伯利亚市25至64岁男性人群(2184名受试者)进行代表性抽样检查。后来,由于无法对心电图进行正确分析,251名男性被排除在研究之外。评估了Q-T间期的长度和离散度以及R-R间期变异性的时间参数。
无论同时进行的流行病学研究的其他临床指标如何,Q-T间期和R-R间期的大小及变异性均与年龄和动脉压相关。R-R间期的长度与体重指数、吸烟及血浆甘油三酯水平独立相关。无论危险因素如何,R-R变异性参数均与冠心病相关。
对Q-T间期和R-R间期持续时间及变异性进行综合分析的扫描研究能有效检测出心律失常和致命事件的高危人群。