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伊朗成年人血脂异常与腰高比、腰围和体重指数的相关性。

Correlation of dyslipidemia with waist to height ratio, waist circumference, and body mass index in Iranian adults.

作者信息

Chehrei Ali, Sadrnia Saeid, Keshteli Ammar Hassanzadeh, Daneshmand Mohammad Ali, Rezaei Jalal

机构信息

Department of pathology, Alzahra University Hospital, Soffeh Street, Isfahan, Iran.

出版信息

Asia Pac J Clin Nutr. 2007;16(2):248-53.

Abstract

Overweight and obesity are increasing problems in many countries and are related to multiple cardiovascular risk factors. Although imaging techniques can determine total body fat and its distribution reliably, anthropometric measurements remain important in clinical practice. The purpose of this study was to determine the association between some anthropometric measurements and dyslipidemia as an important cardiovascular risk factor in Iranian population. A total of 750 subjects (580 females and 170 males) were selected by multistage random sampling from residents of Arak (Iran) and related villages in 2005. None of them had any significant past medical history. Body mass index(BMI), waist circumference(WC), and waist to height ratio(W/Ht) of subjects were measured to identify their relationship with their lipid profile including total cholesterol(TC), triglyceride(TG), high density lipoprotein cholesterol(HDL-C), low density lipoprotein cholesterol(LDL-C), and the ratio of total cholesterol to high density lipoprotein cholesterol(TC/HDL-C). Fasting blood sugar (FBS) was also measured. WC and W/Ht showed greater correlation with TC, TG, LDL-C, TC/HDL-C level than did BMI. Among lipid profile, TG showed the closest correlation with W/Ht (r=0.309, p<0.001) and WC (r=0.308, p<0.001). HDL-C level did not show any statistical relationship with W/Ht, but it was weakly correlated with WC (r=-0.088, p<0.05). None of the indices showed any association with FBS level. It can be concluded that W/Ht and WC can best predict dyslipidemia in an Iranian adult population. We suggest using both W/Ht and WC as inexpensive and easy methods in clinical and epidemiological fields.

摘要

超重和肥胖在许多国家正成为日益严重的问题,并且与多种心血管危险因素相关。尽管成像技术能够可靠地测定全身脂肪及其分布,但人体测量学指标在临床实践中仍然很重要。本研究的目的是确定一些人体测量学指标与血脂异常(作为伊朗人群中一个重要的心血管危险因素)之间的关联。2005年,通过多阶段随机抽样从伊朗阿拉克市及其相关村庄的居民中选取了750名受试者(580名女性和170名男性)。他们均无重大既往病史。测量了受试者的体重指数(BMI)、腰围(WC)和腰高比(W/Ht),以确定它们与血脂谱的关系,血脂谱包括总胆固醇(TC)、甘油三酯(TG)、高密度脂蛋白胆固醇(HDL-C)、低密度脂蛋白胆固醇(LDL-C)以及总胆固醇与高密度脂蛋白胆固醇之比(TC/HDL-C)。还测量了空腹血糖(FBS)。与BMI相比,WC和W/Ht与TC、TG、LDL-C、TC/HDL-C水平的相关性更强。在血脂谱中,TG与W/Ht(r = 0.309,p < 0.001)和WC(r = 0.308,p < 0.001)的相关性最为密切。HDL-C水平与W/Ht无统计学关系,但与WC呈弱相关(r = -0.088,p < 0.05)。这些指标均与FBS水平无关联。可以得出结论,W/Ht和WC能够最好地预测伊朗成年人群中的血脂异常。我们建议在临床和流行病学领域将W/Ht和WC作为廉价且简便的方法使用。

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