Bogyiová E, Siegfried L, Kmetová M, Sándorcínová Z, Liptáková A, Biros E
Institute of Medical Microbiology, School of Medicine, P. J. Safárik University, 040 66 Kosice, Slovakia.
Folia Microbiol (Praha). 2002;47(1):73-7. doi: 10.1007/BF02818569.
Occurrence of cnf1+ E. coli pathogenic strains among extraintestinal E. coli isolates was evaluated to explain an impact of cytotoxic necrotizing factor type 1 (CNF1) in human infections. A total of 120 E. coli isolates were characterized for presence of virulence factors cnf1- and pap--specific sequences by PCR, and the production of alpha-hemolysin using blood agar-plate test. Different association patterns among the detected virulence factors were obtained by comparison of various groups of clinical E. coli isolates. These differences probably reflect a potential impact of CNF1 in the colonization of vaginal environment.
评估肠外大肠杆菌分离株中cnf1+大肠杆菌致病菌株的出现情况，以解释1型细胞毒素坏死因子（CNF1）在人类感染中的影响。通过PCR对120株大肠杆菌分离株进行毒力因子cnf1-和pap-特异性序列检测，并采用血琼脂平板试验检测α-溶血素的产生。通过比较不同组临床大肠杆菌分离株，获得了检测到的毒力因子之间的不同关联模式。这些差异可能反映了CNF1在阴道环境定植中的潜在影响。
