Kuhar I, Grabnar M, Zgur-Bertok D
Department of Biology, Biotechnical Faculty, University of Ljubljana, Slovenia.
FEMS Microbiol Lett. 1998 Jul 15;164(2):243-8. doi: 10.1111/j.1574-6968.1998.tb13093.x.
Twenty-five fecal Escherichia coli strains of serogroups O6 and O18 from patients with and without intestinal infections were analyzed for fimbrial adhesins pap, prs and sfa, hemolysin, cytonecrotic factor, colicins, capsules, antibiotic resistances, plasmid content and some plasmid encoded characteristics. A high percentage of strains expressing P fimbriae was found with an even higher percentage in strains isolated from intestinal infections. A correlation was found between colicinogenicity and P fimbriae production. None of the strains produced hemolysin while 28% had cytonecrotic factor type 1 sequences, demonstrating that cytonecrotic factor type 1 is not always associated with hemolysin production and indicating that the examined strains do not harbor a larger pathogenicity island. Plasmids and plasmid associated characteristics were more frequently associated with the O18 serogroup and chromosomal colicin V genes were found independently of plasmids.
对来自有或无肠道感染患者的25株O6和O18血清型粪便大肠杆菌菌株进行了分析，检测其菌毛黏附素pap、prs和sfa、溶血素、细胞坏死因子、大肠杆菌素、荚膜、抗生素耐药性、质粒含量以及一些质粒编码特性。发现表达P菌毛的菌株比例很高，在从肠道感染中分离出的菌株中比例更高。发现大肠杆菌素生成与P菌毛产生之间存在相关性。没有菌株产生溶血素，而28%的菌株具有1型细胞坏死因子序列，这表明1型细胞坏死因子并不总是与溶血素产生相关，也表明所检测的菌株没有携带更大的致病岛。质粒和质粒相关特性更常与O18血清型相关，并且发现染色体大肠杆菌素V基因与质粒无关。
