Boutin J P, Pages F, Migliani R, Chaignat C L, Ivanoff B
Service de Médecine des Collectivités, Institut de Médecine Tropicale du Service de Santé des Armées, BP 46, Le Pharo, 13998 Marseille-Armées, France.
Med Trop (Mars). 2001;61(6):513-20.
Cholera is an ancestral disease belonging to the mythology of numerous societies. In the last two centuries, seven pandemias have been recorded, in which the spatial and temporal modalities of disease transmission are related to the major technical revolutions of the period. The now ongoing seventh pandemia is by far the longest and most widespread with specific features that raise new challenges and hopes. The authors present the situation at the dawn of the third millennium based on a review of current epidemiological, clinical, therapeutic, diagnostic and vaccinal data. This update shows that the field is progressing and may indeed be standing on the verge of significant breakthroughs for management of the disease and vibrion endemicity.
霍乱是一种古老的疾病，存在于众多社会的神话传说之中。在过去两个世纪里，已记录到七次霍乱大流行，疾病传播的时空模式与当时的重大技术变革相关。目前仍在持续的第七次大流行是迄今为止历时最长、传播最广的一次，具有一些新特点，带来了新的挑战和希望。作者基于对当前流行病学、临床、治疗、诊断及疫苗数据的综述，呈现了第三个千年伊始的情况。这一更新表明该领域正在取得进展，而且在疾病管理和弧菌地方性流行方面可能确实正处在重大突破的边缘。
