Singh M
Department of Pediatrics, Advanced Pediatric Centre, Post Graduate Institute of Medical Education and Research, Chandigarh.
Indian J Pediatr. 2001 Sep;68 Suppl 4:S23-30.
Hospitalization due to acute severe asthma represents a failure in the preventive, long-term as well as home care of asthma. Recognition of danger signs and prompt treatment can prevent the risk of morbidity and mortality of an acute asthma episode. The principle pharmacological management is use of inhaled beta2 sympathomemetrics and systemic steroids given with monitoring of respiratory status with the help of clinical parameters and pulmonary function tests. In patients non responsive to routine management, there is a role of inhaled cholinergic compounds, intravenous magnesium sulphate, and beta2 sympathomemetic infusion. Patients in respiratory failure need intensive care. Carefully managed prognosis of an acute attack of asthma is good.
因急性重度哮喘住院表明哮喘的预防、长期及家庭护理存在不足。识别危险信号并及时治疗可预防急性哮喘发作的发病和死亡风险。主要的药物治疗是使用吸入性β2拟交感神经药和全身性类固醇,并借助临床参数和肺功能测试监测呼吸状态。对于常规治疗无反应的患者,吸入性胆碱能化合物、静脉注射硫酸镁和β2拟交感神经药输注有一定作用。呼吸衰竭的患者需要重症监护。精心管理下,哮喘急性发作的预后良好。