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J Clin Microbiol. 2002 May;40(5):1814-7. doi: 10.1128/JCM.40.5.1814-1817.2002.
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Sensitive and rapid detection of herpes simplex virus and varicella-zoster virus DNA by loop-mediated isothermal amplification.通过环介导等温扩增技术灵敏快速地检测单纯疱疹病毒和水痘-带状疱疹病毒DNA
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Plasma membrane requirements for cell fusion induced by herpes simplex virus type 1 glycoproteins gB, gD, gH and gL.1型单纯疱疹病毒糖蛋白gB、gD、gH和gL诱导细胞融合对质膜的要求。
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Herpes simplex virus glycoprotein K, but not its syncytial allele, inhibits cell-cell fusion mediated by the four fusogenic glycoproteins, gD, gB, gH, and gL.单纯疱疹病毒糖蛋白K，而非其合胞体等位基因，可抑制由四种融合糖蛋白gD、gB、gH和gL介导的细胞间融合。
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Truncation of herpes simplex virus type 2 glycoprotein B increases its cell surface expression and activity in cell-cell fusion, but these properties are unrelated.单纯疱疹病毒2型糖蛋白B的截短增加了其细胞表面表达及在细胞-细胞融合中的活性，但这些特性并无关联。
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Mutations in the 5' end of the herpes simplex virus type 2 latency-associated transcript (LAT) promoter affect LAT expression in vivo but not the rate of spontaneous reactivation of genital herpes.单纯疱疹病毒2型潜伏相关转录物（LAT）启动子5'端的突变影响体内LAT的表达，但不影响生殖器疱疹的自发再激活率。
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[Herpes simplex virus type 1 and 2 (HSV-1,2) DNA detection by PCR during genital herpes].生殖器疱疹期间通过聚合酶链反应检测1型和2型单纯疱疹病毒（HSV-1,2）DNA
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A single amino acid substitution in the cytoplasmic tail of the glycoprotein B of herpes simplex virus 1 affects both syncytium formation and binding to intracellular heparan sulfate.单纯疱疹病毒1型糖蛋白B胞质尾中的单个氨基酸取代既影响合胞体形成，也影响与细胞内硫酸乙酰肝素的结合。
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[Monoclonal antibodies in the diagnosis of infections caused by the herpes simplex virus].[单克隆抗体在单纯疱疹病毒引起的感染诊断中的应用]
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本文引用的文献

1
Cytoplasmic domain of herpes simplex virus gE causes accumulation in the trans-Golgi network, a site of virus envelopment and sorting of virions to cell junctions.单纯疱疹病毒gE的胞质结构域导致其在反式高尔基体网络中积累，反式高尔基体网络是病毒包膜形成以及病毒粒子分拣至细胞连接部位的场所。
J Virol. 2001 Feb;75(4):1928-40. doi: 10.1128/JVI.75.4.1928-1940.2001.
2
Pseudorabies virus glycoprotein M inhibits membrane fusion.伪狂犬病病毒糖蛋白M抑制膜融合。
J Virol. 2000 Aug;74(15):6760-8. doi: 10.1128/jvi.74.15.6760-6768.2000.
3
Aujeszky's disease (pseudorabies) virus: the virus and molecular pathogenesis--state of the art, June 1999.奥耶斯基氏病（伪狂犬病）病毒：病毒与分子发病机制——最新进展，1999年6月
Vet Res. 2000 Jan-Feb;31(1):99-115. doi: 10.1051/vetres:2000110.
4
A cell surface protein with herpesvirus entry activity (HveB) confers susceptibility to infection by mutants of herpes simplex virus type 1, herpes simplex virus type 2, and pseudorabies virus.一种具有疱疹病毒进入活性的细胞表面蛋白（HveB）使细胞对单纯疱疹病毒1型、单纯疱疹病毒2型和伪狂犬病病毒的突变体感染敏感。
Virology. 1998 Jun 20;246(1):179-89. doi: 10.1006/viro.1998.9218.
5
Entry of alphaherpesviruses mediated by poliovirus receptor-related protein 1 and poliovirus receptor.由甲病毒受体相关蛋白1和脊髓灰质炎病毒受体介导的α疱疹病毒的进入
Science. 1998 Jun 5;280(5369):1618-20. doi: 10.1126/science.280.5369.1618.
6
Glycoproteins gB, gD, and gHgL of herpes simplex virus type 1 are necessary and sufficient to mediate membrane fusion in a Cos cell transfection system.单纯疱疹病毒1型的糖蛋白gB、gD和gHgL在Cos细胞转染系统中对于介导膜融合是必需且充分的。
J Virol. 1998 Jan;72(1):873-5. doi: 10.1128/JVI.72.1.873-875.1998.
7
Virus-cell and cell-cell fusion.病毒-细胞融合与细胞-细胞融合。
Annu Rev Cell Dev Biol. 1996;12:627-61. doi: 10.1146/annurev.cellbio.12.1.627.
8
Function of glycoprotein B homologues of the family herpesviridae.疱疹病毒科糖蛋白B同源物的功能。
Infect Agents Dis. 1994 Feb;3(1):9-28.
9
Herpes simplex virus glycoprotein D is sufficient to induce spontaneous pH-independent fusion in a cell line that constitutively expresses the glycoprotein.单纯疱疹病毒糖蛋白D足以在组成性表达该糖蛋白的细胞系中诱导自发的不依赖pH值的融合。
Virology. 1988 Oct;166(2):598-602. doi: 10.1016/0042-6822(88)90533-8.
10
Acid pH-induced fusion of cells by herpes simplex virus glycoproteins gB an gD.单纯疱疹病毒糖蛋白gB和gD在酸性pH值诱导下引发的细胞融合
J Biol Chem. 1990 Apr 5;265(10):5862-8.

从临床标本中分离出一株罕见的具有融合性的2型单纯疱疹病毒毒株。

Recovery of an unusual fusogenic herpes simplex virus type 2 strain from a clinical specimen.

作者信息

Johnson F Brent

机构信息

Department of Microbiology, Brigham Young University, Provo, Utah 84602, USA.

出版信息

J Clin Microbiol. 2002 May;40(5):1814-7. doi: 10.1128/JCM.40.5.1814-1817.2002.

DOI:10.1128/JCM.40.5.1814-1817.2002
PMID:11980965
原文链接:https://pmc.ncbi.nlm.nih.gov/articles/PMC130920/
Abstract

A highly unusual herpes simplex virus type 2 strain, strain Burr, was isolated from a female genital tract clinical specimen. This virus induced remarkably rapid and extensive syncytium formation in Vero cells involving hundreds of cells but was less fusion active in HEp-2 cells, MRC-5 cells, and mink lung cells. Virus-infected cells produced the glycoproteins gB, gC, gD and gE.

摘要

从一份女性生殖道临床标本中分离出了一种极为罕见的2型单纯疱疹病毒毒株——伯尔毒株。该病毒在Vero细胞中诱导形成了极为迅速且广泛的合胞体，涉及数百个细胞，但在HEp-2细胞、MRC-5细胞和貂肺细胞中的融合活性较低。病毒感染的细胞产生了糖蛋白gB、gC、gD和gE。