从临床标本中分离出一株罕见的具有融合性的2型单纯疱疹病毒毒株。
Recovery of an unusual fusogenic herpes simplex virus type 2 strain from a clinical specimen.
作者信息
Johnson F Brent
机构信息
Department of Microbiology, Brigham Young University, Provo, Utah 84602, USA.
出版信息
J Clin Microbiol. 2002 May;40(5):1814-7. doi: 10.1128/JCM.40.5.1814-1817.2002.
Abstract
A highly unusual herpes simplex virus type 2 strain, strain Burr, was isolated from a female genital tract clinical specimen. This virus induced remarkably rapid and extensive syncytium formation in Vero cells involving hundreds of cells but was less fusion active in HEp-2 cells, MRC-5 cells, and mink lung cells. Virus-infected cells produced the glycoproteins gB, gC, gD and gE.
摘要
从一份女性生殖道临床标本中分离出了一种极为罕见的2型单纯疱疹病毒毒株——伯尔毒株。该病毒在Vero细胞中诱导形成了极为迅速且广泛的合胞体，涉及数百个细胞，但在HEp-2细胞、MRC-5细胞和貂肺细胞中的融合活性较低。病毒感染的细胞产生了糖蛋白gB、gC、gD和gE。
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