Allman David, Punt Jennifer A, Izon David J, Aster Jon C, Pear Warren S
Department of Pathology and Laboratory Medicine, The Abramson Family Cancer Research Institute, University of Pennsylvania Medical Center, Philadelphia 19104, USA.
Cell. 2002 Apr;109 Suppl:S1-11. doi: 10.1016/s0092-8674(02)00689-x.
Cell fate decisions in metazoans are regulated by Notch signals. During lymphoid development, Notch influences a series of cell fate decisions involving multipotent progenitors. This review focuses on current views and lingering uncertainties about Notch function in lymphoid cells.
后生动物中的细胞命运决定受Notch信号调控。在淋巴细胞发育过程中，Notch影响一系列涉及多能祖细胞的细胞命运决定。本综述聚焦于目前关于Notch在淋巴细胞中功能的观点以及尚存的不确定性。
