Glynn Shirley M, Marder Stephen R, Liberman Robert P, Blair Karen, Wirshing William C, Wirshing Donna A, Ross Doreen, Mintz Jim
Department of Psychiatry and Biobehavioral Sciences, University of California, Los Angeles and Veteran Affairs Greater Los Angeles Healthcare System, 90073, USA.
Am J Psychiatry. 2002 May;159(5):829-37. doi: 10.1176/appi.ajp.159.5.829.
Although skills training is a validated psychosocial treatment for schizophrenia, generalization of the skills to everyday life has not been optimal. This study evaluated a behaviorally oriented method of augmenting clinic-based skills training in the community with the aim of improving opportunities, encouragement, and reinforcement for outpatients to use their skills in their natural environment.
Sixty-three individuals with schizophrenia were randomly assigned to 60 weeks of clinic-based skills training alone or of clinic-based skills training supplemented with manual-based generalization sessions in the community. Patients were also randomly assigned to receive either haloperidol or risperidone. Therapists' fidelity to the manuals was measured. Patients' acquisition of the skills from pre- to posttraining was evaluated. The primary outcome measures were the Social Adjustment Scale-II and the Quality of Life Scale.
Seventy-one percent of the patients completed the trial. Only six participants experienced psychotic exacerbations during the trial. There was no evidence of a differential medication effect on social functioning. Social functioning improved modestly in both psychosocial conditions over time; participants who received augmented skills training in the community showed significantly greater and/or quicker improvements.
Given judicious and effective antipsychotic medication that limited exacerbations to less than 10% during the trial, a wide range of outpatients with schizophrenia demonstrated substantial learning of illness management and social skills in the clinic. When clinic-based skills training was augmented by in vivo training and consultation, transfer of the skills to everyday life was enhanced. These benefits were established regardless of the medications prescribed.
尽管技能训练是一种已得到验证的针对精神分裂症的心理社会治疗方法,但这些技能在日常生活中的推广效果并不理想。本研究评估了一种以行为为导向的方法,即在社区中强化基于诊所的技能训练,目的是增加门诊患者在自然环境中运用其技能的机会、鼓励和强化。
63名精神分裂症患者被随机分配,分别接受为期60周的单纯基于诊所的技能训练,或接受基于诊所的技能训练并辅以社区中基于手册的推广课程。患者还被随机分配接受氟哌啶醇或利培酮治疗。测量治疗师对手册的依从性。评估患者从训练前到训练后技能的掌握情况。主要结局指标为社会适应量表-II和生活质量量表。
71%的患者完成了试验。在试验期间,只有6名参与者出现精神病性症状加重。没有证据表明药物对社会功能有差异影响。随着时间的推移,在两种心理社会条件下,社会功能均有适度改善;在社区中接受强化技能训练的参与者表现出显著更大和/或更快的改善。
鉴于在试验期间使用了明智且有效的抗精神病药物,将病情加重限制在不到10%,大量精神分裂症门诊患者在诊所中展现出对疾病管理和社交技能的实质性学习。当基于诊所的技能训练通过现场训练和咨询得到强化时,技能向日常生活的转移得到增强。无论所开药物如何,这些益处都得以确立。