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苯丙酮尿症猴子的三种社会偏好测量方法。

Three social-preference measures in PKU monkeys.

作者信息

Chamove A S

出版信息

J Ment Defic Res. 1979 Dec;23(4):265-73. doi: 10.1111/j.1365-2788.1979.tb00861.x.

DOI:10.1111/j.1365-2788.1979.tb00861.x
PMID:119863
Abstract

Of twenty-four one-year-old rhesus, half were brain damaged from excessive phenylalanine (PKU) administered either pre- or post-natally. When compared on three measures of affiliation--(a) a simultaneous forced-choice proximity circus test, (b) a sequential free-operant Butler-box test, and (c) a social group in a playroom--the duration measure of the circus gave the best differentiation between stimulus animals, the Butler box the poorest. Both types of PKU monkeys were found to strongly prefer familiar PKU monkeys, and controls to refer unfamiliar followed by familiar controls. This extends preference research to induced brain damage and confirms behavioural abnormality in PKU macaques, an abnormality detectable by both humans and other monkeys.

摘要

在24只一岁的恒河猴中,一半在出生前或出生后因摄入过量苯丙氨酸(苯丙酮尿症)而脑损伤。当根据三种依恋测量方法进行比较时——(a)同步强制选择接近圈测试,(b)连续自由操作巴特勒箱测试,以及(c)在游戏室中的社会群体——圈测试的持续时间测量在刺激动物之间给出了最好的区分,巴特勒箱测试的区分效果最差。发现两种类型的苯丙酮尿症猴子都强烈偏好熟悉的苯丙酮尿症猴子,而对照组则偏好不熟悉的猴子,其次是熟悉的对照组。这将偏好研究扩展到了诱导性脑损伤,并证实了苯丙酮尿症猕猴的行为异常,这种异常人类和其他猴子都能检测到。

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