Jones L M, Legge M, Goulding A
The School of Physical Education, University of Otago, Dunedin, New Zealand.
Spinal Cord. 2002 May;40(5):230-5. doi: 10.1038/sj.sc.3101286.
Cross-sectional study comparing a group of active spinal cord injured (SCI) males carefully matched for age, height, and weight with active able-bodied male controls.
To compare bone mass of the total body, upper and lower limbs, hip, and spine regions in active SCI and able-bodied individuals.
Outpatient study undertaken in two centres in New Zealand.
Dual energy X-ray absorptiometry (DEXA) scanning was used to determine bone mass. Questionnaires were used to ascertain total time spent in weekly physical activity for each individual. The criterion for entry into the study was regular participation in physical activity of more than 60 min per week, over and above that required for rehabilitation.
Seventeen SCI and their able-bodied controls met our required activity criterion. Bone mineral density (BMD) values of the total body and hip regions were significantly lower in the SCI group than in their controls (P=0.0001). Leg BMD and bone mineral content (BMC) were also significantly lower in the SCI group (P=0.0001). By contrast, lumbar spine BMD and arm BMD and BMC did not differ between the SCI and control groups. Arm BMD and BMC were greater (not significant) than the reference norms (LUNAR database) for both groups.
Intensive exercise regimens may contribute to preservation of arm bone mass in SCI males, but does not prevent demineralisation in the lower body.
横断面研究，将一组年龄、身高和体重经过精心匹配的脊髓损伤（SCI）男性与身体健全的男性对照组进行比较。
比较活跃的脊髓损伤患者和身体健全者全身、上肢和下肢、髋部及脊柱区域的骨量。
在新西兰的两个中心进行的门诊研究。
采用双能X线吸收法（DEXA）扫描来测定骨量。通过问卷调查确定每个人每周进行体育活动的总时长。纳入研究的标准是每周定期参加超过60分钟的体育活动，这超出了康复所需的时间。
17名脊髓损伤患者及其身体健全的对照者符合我们规定的活动标准。脊髓损伤组全身和髋部区域的骨密度（BMD）值显著低于对照组（P = 0.0001）。脊髓损伤组的腿部骨密度和骨矿物质含量（BMC）也显著更低（P = 0.0001）。相比之下，脊髓损伤组和对照组之间的腰椎骨密度、手臂骨密度和BMC没有差异。两组的手臂骨密度和BMC均高于（无显著差异）参考标准（LUNAR数据库）。
强化运动方案可能有助于保留脊髓损伤男性的手臂骨量，但不能防止下身骨质流失。
