Zakrzewska Irena
Zakład Laboratoryjnej Diagnostyki Klinicznej Akademii Medycznej w Białymstoku.
Postepy Hig Med Dosw. 2002;56(1):29-38.
This review describes the physicochemical and biological properties of antigen CA125 and clinical utility of antigen in oncologic diagnostic. CA125 is the most reliable marker for ovarian cancer in clinical practice. Analysis of CA125 values performed by many authors revealed its highest concentrations in serous and endrometrioid histological type. Serial measurements of CA125 are useful in monitoring the response to chemotherapy and follow-up the early detection of recurrent disease of patients with ovarian cancer.
本综述描述了抗原CA125的物理化学和生物学特性以及该抗原在肿瘤诊断中的临床应用。CA125是临床实践中卵巢癌最可靠的标志物。许多作者对CA125值的分析表明,其在浆液性和子宫内膜样组织学类型中浓度最高。连续测量CA125有助于监测化疗反应以及随访卵巢癌患者复发性疾病的早期检测。