López Gómez J M, Jofré R, Cases A
Servicio de Nefrología Hospital General Universitario Gregorio Marañón Dr. Esquerdo, 46 28007 Madrid.
Nefrologia. 2002;22 Suppl 1:59-67.
Cardiovascular complications are the main cause of death in patients with chronic renal disease. These complications are due to two important morphological changes. Firstly, left ventricular hypertrophy together with the changes in the cardiac remodelling and myocardiac fibrosis constitute the lesion with the highest incidence in renal chronic disease. Secondly, disease in the large arteries (macrovascular disease) involve two types lesions: Artherosclerosis, which is characterised by the formation of plaques in the intima arterial membrane and artherosclerosis due to lesions in the media arterial membrane, which causes a loss in elasticity of the arterial tree.
心血管并发症是慢性肾病患者死亡的主要原因。这些并发症归因于两个重要的形态学变化。首先，左心室肥厚以及心脏重塑和心肌纤维化的变化构成了慢性肾病中发病率最高的病变。其次，大动脉疾病（大血管疾病）涉及两种类型的病变：动脉粥样硬化，其特征是在内膜动脉膜中形成斑块，以及由于中膜动脉膜病变导致的动脉粥样硬化，这会导致动脉树弹性丧失。
