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[假舞蹈徐动症作为颈髓病变的表现。病例报告]

[Pseudochoreoathetosis as manifestation of cervical cord lesion. Case report].

作者信息

Fiszer U, Cichy S, Zaborski J, Pastuszko M, Członkowska A

机构信息

II Kliniki Neurologii Instytutu Psychiatrii i Neurologii, Warszawie.

出版信息

Neurol Neurochir Pol. 2001 Nov-Dec;35(6):1141-8.

Abstract

The involuntary movements of choreoathetotic type are commonly regarded as a sign of basal ganglia lesion. However, such movements can also occur in pathological processes involving the cervical spinal cord. This condition is referred to as pseudochoreoathetosis. Involuntary movements can be related to lack of proper coordination between agonist and antagonist muscles, their simultaneous activation due to impairment of reciprocal inhibition. The characteristic feature of pseudochoreoathetosis is proprioceptive sensory loss. In this paper we present 4 patients who developed various involuntary limb movements in early stage of the disease. Lesions in the cervical spinal cord were confirmed by MRI. In case 1 the cause was astrocytoma, in cases 2 and 3--demyelination, in case 4 the precise character of the lesion could not be established. Pseudochoreoathetosis is a rare condition which often remains unrecognized. The presented cases emphasise the importance of early and correct diagnosis leading to proper therapeutical procedure.

摘要

舞蹈样徐动型的不自主运动通常被视为基底神经节病变的体征。然而,此类运动也可发生于涉及颈脊髓的病理过程中。这种情况被称为假性舞蹈徐动症。不自主运动可能与主动肌和拮抗肌之间缺乏适当协调有关,由于交互抑制受损导致它们同时激活。假性舞蹈徐动症的特征性表现是本体感觉丧失。在本文中,我们报告了4例在疾病早期出现各种肢体不自主运动的患者。MRI证实了颈脊髓病变。病例1的病因是星形细胞瘤,病例2和3是脱髓鞘,病例4中病变的确切性质无法确定。假性舞蹈徐动症是一种罕见病症,常未被识别。所报告的病例强调了早期正确诊断对于采取适当治疗措施的重要性。

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