Beech J
Vet Pathol. 1975;12(3):157-64. doi: 10.1177/030098587501200301.
Tracheobronchial aspirates were obtained from 27 normal horses and from 57 horses with respiratory disease. Aspirates from normal horses contained mainly ciliated columnar epithelial cells, mononuclear cells, a few neutrophils and mucus. Aspirates from horses with acute suppurative bronchopneumonias or chronic bronchiolitis had predominantly neutrophils and usually large amounts of mucus; in severe suppurative inflammatory diseases, many of the cells were degenerated, and there were coils of fibrinous material resembling Curschmann's spirals. Eosinophils were rarely found, even from horses with histories suggestive of allergic respiratory disease. Aspirates from horses with epistaxis frequently had macrophages with intracytoplasmic green globules (hemosiderin). Tracheobronchial aspirates occasionally revealed subclinical lung disease. Four horses with no clinical signs of lung disease and lungs that were unremarkable on percussion and normal on auscultation had adpirates suggestive of inflammation; histologic examination confirmed bronchiolitis.
从27匹正常马和57匹患有呼吸道疾病的马身上获取气管支气管吸出物。正常马的吸出物主要包含纤毛柱状上皮细胞、单核细胞、少量中性粒细胞和黏液。患有急性化脓性支气管肺炎或慢性细支气管炎的马的吸出物中主要是中性粒细胞,通常还有大量黏液;在严重的化脓性炎症疾病中,许多细胞发生变性,并且存在类似库施曼螺旋体的纤维状物质卷曲。即使是有过敏性呼吸道疾病病史的马,也很少发现嗜酸性粒细胞。鼻出血马的吸出物中经常有含有胞质内绿色小球(含铁血黄素)的巨噬细胞。气管支气管吸出物偶尔会揭示亚临床肺部疾病。四匹没有肺部疾病临床症状、叩诊肺部无异常且听诊正常的马,其吸出物提示有炎症;组织学检查证实为细支气管炎。