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[不饱和脂肪酸对过热葵花籽油致癌活性的影响]

[Effect of unsaturated fatty acids on the carcinogenic activity of overheated sunflower seed oil].

作者信息

Vysheslavova M Ia, Kozlova I N

出版信息

Vopr Onkol. 1975;21(4):40-4.

PMID:1198985
Abstract

Non-pedigree rats were injected subcutaneously either overheated oil or the oil and one of unsaturated fatty acids (linoleic, linolenic, oleic acids), or overheated oil and fresh oil. The greatest number of tumors in earlier terms occurred in the group of rats not receiving fatty acids. In simultaneous injection of overheated sunflower oil and fatty acids (oleic and linolenic), as well as fresh oil, tumors would arise considerably more rarely. Whereas, in injection of overheated sunflower oil and linoleic acid tumors did not arise at all. The mechanism of an inhibitory action of fatty acids on tumor development is discussed.

摘要

对非纯种大鼠皮下注射过热油、过热油与一种不饱和脂肪酸(亚油酸、亚麻酸、油酸)的混合物,或过热油与新鲜油的混合物。早期肿瘤数量最多的是未接受脂肪酸的大鼠组。同时注射过热的向日葵油和脂肪酸(油酸和亚麻酸)以及新鲜油时,肿瘤出现的几率要低得多。而注射过热的向日葵油和亚油酸时则根本不会出现肿瘤。文中讨论了脂肪酸对肿瘤发展的抑制作用机制。

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