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英国14545名75岁及以上代表性样本的老年抑郁量表评分:社区老年人评估与管理医学研究委员会试验结果

Geriatric Depression Scale Scores in a representative sample of 14 545 people aged 75 and over in the United Kingdom: results from the MRC Trial of Assessment and Management of Older People in the Community.

作者信息

Osborn David P J, Fletcher Astrid E, Smeeth Liam, Stirling Susan, Nunes Maria, Breeze Elizabeth, Siu-Woon Ng Edmond, Bulpitt Christopher J, Jones Dee, Tulloch Alistair

机构信息

Department of Epidemiology, London School of Hygiene and Tropical Medicine, London, UK.

出版信息

Int J Geriatr Psychiatry. 2002 Apr;17(4):375-82. doi: 10.1002/gps.613.

Abstract

BACKGROUND

The 15-item Geriatric Depression Scale (GDS-15) is recommended for screening older people, but there are no large epidemiological studies using this instrument in the UK. We describe the age and sex distribution of GDS-15 scores in the largest ever UK sample of people aged 75 and over.

METHOD

We used cross-sectional data from the MRC Trial of the Assessment and Management of Older People in the Community. The GDS-15 was offered to a representative sample of UK people aged 75 and over. Proportions of people attaining thresholds on the GDS-15 were calculated by age group and sex. Crude Odds ratios (ORs) for the effect of age and sex were calculated and the sex/age adjusted ORs estimated using logistic regression for surveys, at three GDS-15 thresholds.

RESULTS

Of 21 241 (71.2%; 95% Confidence intervals (CI): 67.9-74.3) eligible people, 15 126 received the assessment including the GDS-15. Of these, 14 545 (96.2%; 94.7-97.2) completed > or =13 GDS-15 answers and were included in the study. Scores showed a marked right skew, with a median of 2 (interquartile range: 1-3; range: 0-14). 34.6% (95% CI: 32.1-37.3) people scored > or =3, 8.0% (6.9-9.2) scored > or =6 and 3.1% (2.5-3.7) scored > or =8. Women were significantly more likely to score above all three thresholds than men, as were older participants.

CONCLUSIONS

Depression may be common in later life. The data provide a national picture of the numbers of older people who will score positively for depression in health screens which include the GDS-15, as recommended by the Royal College of General Practitioners.

摘要

背景

15项老年抑郁量表(GDS - 15)被推荐用于老年人筛查,但在英国尚无使用该工具的大型流行病学研究。我们描述了英国有史以来最大规模的75岁及以上人群样本中GDS - 15评分的年龄和性别分布情况。

方法

我们使用了社区中老年人评估与管理的医学研究委员会试验的横断面数据。向英国75岁及以上具有代表性的人群样本发放GDS - 15。按年龄组和性别计算达到GDS - 15阈值的人群比例。计算年龄和性别的粗比值比(OR),并使用逻辑回归对调查结果在三个GDS - 15阈值下估计性别/年龄调整后的OR。

结果

在21241名符合条件的人群中(71.2%;95%置信区间(CI):67.9 - 74.3),15126人接受了包括GDS - 15在内的评估。其中,14545人(96.2%;94.7 - 97.2)完成了≥13个GDS - 15问题的回答并被纳入研究。评分呈明显的右偏态,中位数为2(四分位间距:1 - 3;范围:0 - 14)。34.6%(95%CI:32.1 - 37.3)的人得分≥3,8.0%(6.9 - 9.2)得分≥6,3.1%(2.5 - 3.7)得分≥8。女性比男性更有可能在所有三个阈值以上得分,老年参与者也是如此。

结论

抑郁症在晚年可能很常见。这些数据提供了一幅全国性的图景,展示了在按照皇家全科医师学院的建议进行的包括GDS - 15的健康筛查中,抑郁筛查呈阳性的老年人数量。

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