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[关于对兔心肌中阶梯现象和增强现象解释的各种批判性评论]

[Various critical comments on the interpretation of staircase- and potentiation phenomena in the rabbit heart muscle].

作者信息

Wussling M, Szymanski G

出版信息

Acta Biol Med Ger. 1975;34(7):1159-66.

PMID:1199637
Abstract

Some critical remarks on the interpretation of staircase and potentiation phenomena (rabbit heart muscle). Isometric contractions of rabbit papillary muscles and atrial strips were investigated at temperatures from 13.2 degrees C to 35 degrees C after rests of different duration at constant stimulation frequency before rest, in a period after rest and in a transition phase following a step of stimulation frequency. Changes in potentiation as well as changes in dynamics after rest and dynamics after steps of stimulation frequency are caused by lowering the temperature. Any hypothesis on the subject of Ca-movements between intracellular stores would have to account for changes in potentiation, staircase phenomena and the development of after-contractions at low temperatures.

摘要

关于阶梯现象和增强现象解释的一些批判性评论(兔心肌)。在13.2摄氏度至35摄氏度的温度下,对兔乳头肌和心房肌条进行等长收缩研究,实验包括在休息前以恒定刺激频率进行不同时长的休息后、休息期间以及刺激频率改变后的过渡阶段。休息后增强的变化以及刺激频率改变后的动力学变化是由温度降低引起的。任何关于细胞内储存库之间钙运动的假设都必须考虑到低温下增强的变化、阶梯现象以及后收缩的发展。

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