Larsson B, Hamberger L, Rybo G
Acta Obstet Gynecol Scand. 1975;54(4):315-8. doi: 10.3109/00016347509156760.
In a series of 43 healthy women menstrual blood loss was determined before and after insertion of copper IUD (Gravigard). The menstrual blood loss before insertion was compared with the blood loss 1, 2, 3, 4, 5, 6, 7 and 12 months after insertion. An increase amounting to approximately 20 ml per period without significant variations during the study was recorded. No significant influence upon serum iron and TIBC was found in 15 of the subjects selected by random. Compared with plastic IUD's the tested copper IUD causes a less pronounced increase of the menstrual blood loss. The menstrual blood loss in a small group of women with menorrhagia was determined before and up to 5 months after insertion of copper IUD. No aggravation of the menorrhagia was however recorded in this group.
在43名健康女性中,测定了放置铜制宫内节育器(Gravigard)前后的月经量。将放置前的月经量与放置后1、2、3、4、5、6、7和12个月的月经量进行比较。记录到每个月经周期增加约20毫升,且在研究期间无显著变化。在随机选择的15名受试者中,未发现对血清铁和总铁结合力有显著影响。与塑料宫内节育器相比,所测试的铜制宫内节育器导致的月经量增加不太明显。在一小群月经过多的女性中,测定了放置铜制宫内节育器前后直至5个月的月经量。然而,该组未记录到月经过多加重的情况。