How selenium has altered our understanding of the genetic code.
作者信息
Hatfield Dolph L, Gladyshev Vadim N
机构信息
Molecular Biology of Selenium Section, Basic Research Laboratory, Center for Cancer Research, National Cancer Institute, National Institutes of Health, Bethesda, Maryland 20892, USA.
出版信息
Mol Cell Biol. 2002 Jun;22(11):3565-76. doi: 10.1128/MCB.22.11.3565-3576.2002.
Abstract
摘要
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本文引用的文献
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Selenoprotein R is a zinc-containing stereo-specific methionine sulfoxide reductase.硒蛋白R是一种含锌的立体特异性蛋氨酸亚砜还原酶。
Proc Natl Acad Sci U S A. 2002 Apr 2;99(7):4245-50. doi: 10.1073/pnas.072603099.
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Mammalian selenoprotein in which selenocysteine (Sec) incorporation is supported by a new form of Sec insertion sequence element.哺乳动物硒蛋白，其中硒代半胱氨酸（Sec）的掺入由一种新型的Sec插入序列元件支持。
Mol Cell Biol. 2002 Mar;22(5):1402-11. doi: 10.1128/MCB.22.5.1402-1411.2002.
3
Mass spectrometric characterization of full-length rat selenoprotein P and three isoforms shortened at the C terminus. Evidence that three UGA codons in the mRNA open reading frame have alternative functions of specifying selenocysteine insertion or translation termination.全长大鼠硒蛋白P及三种C末端截短的异构体的质谱表征。有证据表明，mRNA开放阅读框中的三个UGA密码子具有指定硒代半胱氨酸插入或翻译终止的替代功能。
J Biol Chem. 2002 Apr 12;277(15):12749-54. doi: 10.1074/jbc.M111462200. Epub 2002 Jan 30.
4
Peptide methionine sulfoxide reductase: structure, mechanism of action, and biological function.肽甲硫氨酸亚砜还原酶：结构、作用机制及生物学功能
Arch Biochem Biophys. 2002 Jan 15;397(2):172-8. doi: 10.1006/abbi.2001.2664.
5
6
Methionine sulfoxide reductase (MsrA) is a regulator of antioxidant defense and lifespan in mammals.甲硫氨酸亚砜还原酶（MsrA）是哺乳动物抗氧化防御和寿命的调节因子。
Proc Natl Acad Sci U S A. 2001 Nov 6;98(23):12920-5. doi: 10.1073/pnas.231472998. Epub 2001 Oct 23.
7
Evolution of selenocysteine-containing proteins: significance of identification and functional characterization of selenoproteins.含硒代半胱氨酸蛋白质的进化：硒蛋白鉴定与功能表征的意义
Biofactors. 2001;14(1-4):87-92. doi: 10.1002/biof.5520140112.
8
In silico identification of novel selenoproteins in the Drosophila melanogaster genome.在果蝇基因组中通过计算机模拟鉴定新型硒蛋白
EMBO Rep. 2001 Aug;2(8):697-702. doi: 10.1093/embo-reports/kve151.
9
Interplay between termination and translation machinery in eukaryotic selenoprotein synthesis.真核生物硒蛋白合成中终止与翻译机制之间的相互作用。
J Mol Biol. 2001 Jul 20;310(4):699-707. doi: 10.1006/jmbi.2001.4809.
10
Heterologous expression of archaeal selenoprotein genes directed by the SECIS element located in the 3' non-translated region.由位于3'非翻译区的硒代半胱氨酸插入序列元件指导的古菌硒蛋白基因的异源表达。
Mol Microbiol. 2001 May;40(4):900-8. doi: 10.1046/j.1365-2958.2001.02433.x.
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