[侧索肌萎缩硬化症患者脑血清抗体在兔中枢神经系统中的固定规律]
[Regularities of fixation of brain serum antibodies from patients with lateral amyotrophic sclerosis in rabbit CNS].
作者信息
Musaeva L S, Gannyshkina I V, Zavalishin I A, Markova E D, Ivanova-Smolenskaia I A
出版信息
Patol Fiziol Eksp Ter. 2002 Jan-Mar(1):10-4.
Kuhns' indirect immunofluorescent test was used to study fixation of serum brain antibodies (Ab) of patients with bulbar, cervicothoracic, lumbosacral lateral amyotropic sclerosis (LAS) on brain sections of rabbits. The disease is characterized by formation of brain Ab complementary to various structures of nervous and glial cells, myelin of fibers from different conducting systems, vessels which exhibit both common and individual antigenic properties. It was found that fixation of antineuronal, antimyelin brain Ab of patients with bulbar, cervicothoracic and lumbosacral LAS in different CNS structures varies.
库恩斯间接免疫荧光试验用于研究延髓、颈胸段、腰骶段侧索肌萎缩性硬化症（LAS）患者血清脑抗体（Ab）在兔脑切片上的固定情况。该疾病的特征是形成与神经和神经胶质细胞的各种结构、来自不同传导系统的纤维髓鞘、具有共同和个体抗原特性的血管互补的脑抗体。研究发现，延髓、颈胸段和腰骶段LAS患者的抗神经元、抗髓鞘脑抗体在不同中枢神经系统结构中的固定情况各不相同。
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