部分回肠旁路手术治疗高脂血症。

The partial ileal bypass operation in treatment of the hyperlipidemias.

作者信息

Buchwald H, Moore R B, Varco R L

出版信息

Adv Exp Med Biol. 1975;63:221-30. doi: 10.1007/978-1-4684-3258-9_14.

PMID:1199864

Abstract

Partial ileal bypass is, today, the single most effective means available for lowering the plasma lipids, in particular the plasma cholesterol concentration. The cholesterol lowering effect of this procedure is universally lasting; response escape or rebound of lipid levels has not occurred. The operation is safe. In addition, the obligatory benefits of this mode of therapy make it attractive as a therapeutic alternative, especially in a young and asymptomatic population. We do not advocate this operation as the treatment of choice for all hyperlipidemic individuals. It may be the treatment of choice for certain patients with hyperlipidemia.

摘要

如今，部分回肠旁路术是降低血脂，尤其是降低血浆胆固醇浓度的最有效手段。该手术降低胆固醇的效果持久；尚未出现血脂水平的反应逃逸或反弹。手术安全。此外，这种治疗方式带来的必然益处使其成为一种有吸引力的治疗选择，尤其是对于年轻且无症状的人群。我们并不主张将此手术作为所有高脂血症患者的首选治疗方法。它可能是某些高脂血症患者的首选治疗方法。