Roland Per E
Division of Brain Research, Dept of Neuroscience, A3:3, Retzius vaeg 8, Karolinska Institute, S-171 77 Stockholm, Sweden.
Trends Neurosci. 2002 Apr;25(4):183-90. doi: 10.1016/s0166-2236(00)02125-1.
Recent physiological evidence shows that in response to stimuli and preceding motor activity, large fields of the upper layers of the cerebral cortex depolarize. It is argued that this finding is a general one and that these dynamic depolarization fields represent the computational elements of the cerebral cortex. Each depolarization field engages many more neurons than do columns and hyper-columns. These fields can be explained by cooperative neuronal computing in layers I-III of the cortex. In these layers, the computing modes might be general for all parts of the cerebral cortex and be sufficiently flexible to handle all sorts of cortical computations, including perception, memory storage, memory retrieval, thought and the production of behavior.
最近的生理学证据表明，在对刺激和先前的运动活动作出反应时，大脑皮层上层的大片区域会发生去极化。有人认为，这一发现具有普遍性，这些动态去极化场代表了大脑皮层的计算元件。每个去极化场涉及的神经元比柱状结构和超柱状结构要多得多。这些场可以通过皮层I-III层中神经元的协同计算来解释。在这些层中，计算模式可能对大脑皮层的所有部分都是通用的，并且具有足够的灵活性来处理各种皮层计算，包括感知、记忆存储、记忆检索、思维和行为产生。
