Lyons Frances, Hanley J Richard, Kay Janice
Department of Psychology, University of Essex, Colchester, UK.
Cortex. 2002 Feb;38(1):23-35. doi: 10.1016/s0010-9452(08)70636-1.
This paper describes the case of an anomic patient (FH) who is impaired at naming pictures of objects but has no difficulties in recalling the names of familiar people. Even though his performance on McKenna's (1997) Category Specific Naming Test was at the first percentile, he consistently recalled the names of familiar people as successfully as controls. It is argued that the pattern of performance displayed by FH represents a much clearer double dissociation with proper name anomia than any case previously reported (Cipolotti et al., 1993; Semenza and Sgaramella, 1993). FH is unable to provide detailed semantic information about many of the objects that he cannot name, even though he can recall semantic information about familiar people. Consequently his case appears to represent the mirror image of the proper name anomic patient (APA) described by Miceli et al. (2000) who was unable to recall detailed semantic information about many of the people she was unable to name. Further investigation of FH's anomia revealed impairments in retrieving both common nouns and verbs, and difficulties in retrieving and comprehending geographical names. It is argued that FH's preserved ability to name and recall biographical information about people supports the view that knowledge about familiar people may be subserved by its own dedicated neural subsystem (Kay and Hanley, 1999; Miceli et al., 2000; Gentileschi et al., 2001).
本文描述了一位命名性失语患者(FH)的病例,该患者在命名物体图片方面存在障碍,但回忆熟人的名字却没有困难。尽管他在麦肯纳(1997年)的类别特异性命名测试中的表现处于第一百分位,但他回忆熟人名字的成功率与对照组相当。有人认为,FH所表现出的表现模式与专有名词性失语相比,呈现出比之前报道的任何病例(西波洛蒂等人,1993年;塞门扎和斯加拉梅拉,1993年)都更为清晰的双重分离。FH无法为许多他叫不出名字的物体提供详细的语义信息,尽管他能回忆起关于熟人的语义信息。因此,他的病例似乎代表了米凯利等人(2000年)所描述的专有名词性失语患者(APA)的镜像,后者无法回忆起许多她叫不出名字的人的详细语义信息。对FH失语症的进一步研究发现,他在检索普通名词和动词方面存在障碍,在检索和理解地名方面也有困难。有人认为,FH保留的命名和回忆人物传记信息的能力支持了这样一种观点,即关于熟人的知识可能由其自身专门的神经子系统提供支持(凯和汉利,1999年;米凯利等人,2000年;金泰莱斯基等人,2001年)。