菠菜中可能存在的抗肿瘤启动子及其不同品种间含量的比较。

Possible antitumor promoters in Spinacia oleracea (spinach) and comparison of their contents among cultivars.

作者信息

Wang Rong, Furumoto Toshio, Motoyama Koichiro, Okazaki Katsuichiro, Kondo Akira, Fukui Hiroshi

机构信息

Department of Biochemistry and Food Science, Faculty of Agriculture, Kagawa University, Japan.

出版信息

Biosci Biotechnol Biochem. 2002 Feb;66(2):248-54. doi: 10.1271/bbb.66.248.

DOI:10.1271/bbb.66.248

PMID:11999395

Abstract

Spinach leaves were found to contain two potent antitumor promoters as detected by the activity against tumor promoter-induced Epstein-Barr virus activation. The active components were identified as 1-O-alpha-linolenoyl-2-O-(7Z,10Z,13Z)-hexadecatrienoyl-3-O-beta-D-galactopyranosyl-sn-glycerol and 1,2-di-O-alpha-linolenoyl-3-O-beta-D-galactopyranosyl-sn-glycerol by spectroscopic data and some chemical and enzymatic reactions. Their contents significantly varied with the cultivar and with the culture conditions.

摘要

通过检测对肿瘤启动子诱导的爱泼斯坦-巴尔病毒激活的活性，发现菠菜叶含有两种强效抗肿瘤启动子。通过光谱数据以及一些化学和酶促反应，活性成分被鉴定为1-O-α-亚麻酸基-2-O-(7Z,10Z,13Z)-十六碳三烯酸基-3-O-β-D-吡喃半乳糖基-sn-甘油和1,2-二-O-α-亚麻酸基-3-O-β-D-吡喃半乳糖基-sn-甘油。它们的含量因品种和培养条件而有显著差异。