Suzuki Yoshiyuki, Ito Jun, Hasegawa Masatoshi, Katano Susumu, Saito Junichi, Ito Hideaki
Department of Radiology, Maebashi Red Cross Hospital, Japan.
Radiat Med. 2002 Jan-Feb;20(1):37-9.
Recently, a combination of local irradiation and chemotherapy has been suggested as a standardized treatment for localized lymphoma. However, it has been difficult to establish a standard treatment for localized primary breast lymphoma simply because of its rarity. We report two cases of primary breast lymphoma successfully treated with a combination therapy including local radiation therapy. A 46-year-old woman with stage I primary breast lymphoma was irradiated with 30 Gy to the involved breast by 4 MV X-rays and 9 Gy to the involved field by electron beam after tumorectomy. Then three cycles of CHOP therapy were performed. She has been well and has shown no evidence of disease for 58 months. A 72-year-old woman with stage II primary breast lymphoma was treated with three cycles of CHOP therapy followed by irradiation with 40 Gy per breast by 4 MV X-rays. She is well and has been disease-free for 49 months. We suggest that a combination of local irradiation and short course of chemotherapy can be useful in the treatment of primary breast lymphoma.
最近，局部放疗和化疗联合已被推荐作为局限性淋巴瘤的标准化治疗方法。然而，由于原发性乳腺淋巴瘤极为罕见，很难确立其标准化治疗方案。我们报告了两例原发性乳腺淋巴瘤患者成功接受包括局部放疗在内的联合治疗的病例。一名46岁的I期原发性乳腺淋巴瘤女性患者，在肿瘤切除术后，接受4MV X射线对患侧乳房照射30Gy以及电子束对受累野照射9Gy。随后进行了三个周期的CHOP化疗。她情况良好，58个月来未发现疾病迹象。一名72岁的II期原发性乳腺淋巴瘤女性患者，先接受三个周期的CHOP化疗，随后接受4MV X射线对每侧乳房照射40Gy。她情况良好，49个月来无疾病复发。我们认为局部放疗和短程化疗联合可能对原发性乳腺淋巴瘤的治疗有效。
