Read R C, Thompson B W
Am J Surg. 1975 Dec;130(6):682-7. doi: 10.1016/0002-9610(75)90420-1.
One hundred and eighty-seven men, aged twenty to eighty years with an average of forty-eight years, underwent surgery for perforated duodenal ulcer. Seventeen received an immediate definitive procedure; none died. Nine (5 per cent) of the remaining 170 who had omentopexy died one to fifteen days postoperatively. They were older and waited longer. One hundred and twenty-one patients (76 per cent) were adequately followed. Thirty-nine (32 per cent) had "acute" perforation and eighty-two had "chronic" perforation. Twenty-four (30 per cent) of the latter underwent definitive operation within three months without mortality. Overall, 25 per cent of the ninety-nine patients followed after omentopexy required reoperation within twelve months. However, only three (8 per cent) of the thirty-nine with "acute" perforation required operation as compared with twenty-one (37 per cent) of the fifty-eight with "chronic" perforation. The main reason for early operation in the "chronic" group was obstruction; 21 per cent failed to empty their stomach immediately or soon after omentopexy and half as many either had pain or bled severely within twelve months and also required reoperation. The "acute" and "chronic" groups continued to differ in their need for further operation. Overall, 57 per cent of the ninety-seven patients required a definitive operation one to twenty-four years later. However, only ten of the thirty-nine patients (26 per cent) in the "acute" group required definitive operation as compared with forty-five of the fifty-eight patients (77 per cent) in the "chronic" group. Outlet obstruction of the stomach was the main indication for definitive surgery in twenty-six of the fifty-five (47 per cent) reoperations. This high incidence of gastric obstruction after omentopexy was not peculiar to our institution since, over the past six years, eighteen patients having omentopexy elsewhere had to be operated on for this complication. We recommend that patients with "chronic" perforation should not undergo omentopexy but rather immediate vagotomy and a drainage procedure.
187名年龄在20至80岁之间(平均48岁)的男性接受了十二指肠溃疡穿孔手术。17人接受了即刻确定性手术,无死亡病例。其余170名接受网膜固定术的患者中有9人(5%)在术后1至15天死亡。他们年龄较大,等待时间较长。121名患者(76%)得到了充分随访。39名(32%)为“急性”穿孔,82名为“慢性”穿孔。后者中有24名(30%)在三个月内接受了确定性手术,无死亡病例。总体而言,网膜固定术后接受随访的99名患者中有25%在12个月内需要再次手术。然而,39名“急性”穿孔患者中只有3名(8%)需要手术,而58名“慢性”穿孔患者中有21名(37%)需要手术。“慢性”组早期手术的主要原因是梗阻;21%的患者在网膜固定术后立即或不久后胃排空障碍,12个月内有一半患者出现疼痛或严重出血,也需要再次手术。“急性”组和“慢性”组在进一步手术需求方面仍存在差异。总体而言,97名患者中有57%在1至24年后需要进行确定性手术。然而,“急性”组的39名患者中只有10名(26%)需要确定性手术,而“慢性”组的58名患者中有45名(77%)需要确定性手术。胃出口梗阻是55例(47%)再次手术中确定性手术的主要指征。网膜固定术后胃梗阻的高发生率并非我们机构所特有,因为在过去六年中,其他地方接受网膜固定术的18名患者因该并发症不得不接受手术。我们建议,“慢性”穿孔患者不应接受网膜固定术,而应立即进行迷走神经切断术和引流手术。