Morita Y, Miyamoto T, Horiuchi Y, Oshima S, Katsuhata A
Ann Allergy. 1975 Dec;35(6):361-6.
The sera from 99 Japanese asthmatic subjects were studied for the allergenic similarity between house dust and the House-dust Mite, Dermatophagoides farinae Hughes, 1961. A close correlation (correlation coefficient 0.92, P less than 0.01) was obtained between house dust and the mite with the radioallergosorbent test (RAST). High correlation was not noted between house dust and other allergens such as smoky brown cockroach, Periplaneta fuliginosa, Aspergillus, book lice, Liposcelis bostricophilus, Cheyletus malaccensis and Tribolium confusum. IgE antibody to the mite reduced significantly after the incubation of the sera with house dust and IgE antibody to house dust reduced markedly after the incubation of the sera with the mite. These results further support the view that the mite is the most important allergenic component in house dust.
对99名日本哮喘患者的血清进行了研究，以探讨屋尘与屋尘螨（1961年命名的粉尘螨）之间的过敏原相似性。通过放射变应原吸附试验（RAST），发现屋尘与螨虫之间存在密切相关性（相关系数0.92，P小于0.01）。屋尘与其他过敏原如黑胸大蠊、烟曲霉、嗜卷书虱、马六甲肉食螨和杂拟谷盗之间未发现高度相关性。血清与屋尘孵育后，针对螨虫的IgE抗体显著降低；血清与螨虫孵育后，针对屋尘的IgE抗体显著降低。这些结果进一步支持了螨虫是屋尘中最重要的过敏原成分这一观点。
